Multimodal Large Language Models (MLLMs), trained primarily on English-centric data, frequently generate culturally inappropriate or misaligned responses in cross-cultural settings. To mitigate this, we introduce the task of cross-cultural knowledge insertion, which focuses on adapting models to specific cultural contexts while preserving their original behavior in other cultures. To facilitate research in this area, we introduce CrossCult-KIBench, a comprehensive evaluation benchmark for assessing both the effectiveness of knowledge insertion and its unintended side effects on non-target cultures. The benchmark includes 9,800 image-grounded cases covering 49 culturally relevant visual scenarios across English, Chinese, and Arabic language-culture groups. It supports evaluation in both single-insert and sequential-insert settings. We also propose Memory-Conditioned Knowledge Insertion (MCKI) as a baseline method. MCKI retrieves relevant cultural knowledge from an external memory using frozen MLLM representations, prepending matched entries as conditional prompts when applicable. Extensive experiments on CrossCult-KIBench reveal that current approaches struggle to balance effective cultural adaptation with behavioral preservation, highlighting a key challenge in developing culturally-aware MLLMs. Our work thus underscores an important research direction for developing more culturally adaptive and responsible MLLMs.