Large language models (LLMs) are used by over a billion people globally, most often to assist with writing. In this work, we demonstrate that LLMs not only alter the voice and tone of human writing, but also consistently alter the intended meaning. First, we conduct a human user study to understand how people actually interact with LLMs when using them for writing. Our findings reveal that extensive LLM use led to a nearly 70% increase in essays that remained neutral in answering the topic question. Significantly more heavy LLM users reported that the writing was less creative and not in their voice. Next, using a dataset of human-written essays that was collected in 2021 before the widespread release of LLMs, we study how asking an LLM to revise the essay based on the human-written feedback in the dataset induces large changes in the resulting content and meaning. We find that even when LLMs are prompted with expert feedback and asked to only make grammar edits, they still change the text in a way that significantly alters its semantic meaning. We then examine LLM-generated text in the wild, specifically focusing on the 21% of AI-generated scientific peer reviews at a recent top AI conference. We find that LLM-generated reviews place significantly less weight on clarity and significance of the research, and assign scores that, on average, are a full point higher.These findings highlight a misalignment between the perceived benefit of AI use and an implicit, consistent effect on the semantics of human writing, motivating future work on how widespread AI writing will affect our cultural and scientific institutions.