Despite advances in Neural Machine Translation (NMT), low-resource languages like Tigrinya remain underserved due to persistent challenges, including limited corpora, inadequate tokenization strategies, and the lack of standardized evaluation benchmarks. This paper investigates transfer learning techniques using multilingual pretrained models to enhance translation quality for morphologically rich, low-resource languages. We propose a refined approach that integrates language-specific tokenization, informed embedding initialization, and domain-adaptive fine-tuning. To enable rigorous assessment, we construct a high-quality, human-aligned English-Tigrinya evaluation dataset covering diverse domains. Experimental results demonstrate that transfer learning with a custom tokenizer substantially outperforms zero-shot baselines, with gains validated by BLEU, chrF, and qualitative human evaluation. Bonferroni correction is applied to ensure statistical significance across configurations. Error analysis reveals key limitations and informs targeted refinements. This study underscores the importance of linguistically aware modeling and reproducible benchmarks in bridging the performance gap for underrepresented languages. Resources are available at https://github.com/hailaykidu/MachineT_TigEng and https://huggingface.co/Hailay/MachineT_TigEng