Speculative decoding (SD) has become a popular technique to accelerate Large Language Model (LLM) inference, yet its real-world effectiveness remains unclear as prior evaluations rely on research prototypes and unrealistically small batch sizes. We present, to our knowledge, the first systematic study of SD on a production-grade and widely deployed inference engine (vLLM), covering multiple SD variants ($n$-gram, EAGLE/EAGLE-3, Draft-Model, Multi-Token Prediction) across diverse workloads, model scales, and batch sizes. We analyze key factors governing SD performance, and quantify a theoretical upper bound on SD speedup. Our results show that verification by the target model dominates the execution, while acceptance length varies markedly across output token positions, requests, and datasets. Comparing measured performance with theoretical bounds reveals substantial gaps between observed and theoretical upper bounds, and we leverage this observation to highlight new research opportunities that our study opens up in improving SD.