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Palo Alto Networks Blog

New Executive Order Accelerates Post-Quantum Readiness Amid the Cryptographic Reset Built to Last: What Stonehenge Teaches us About IT Architecture & Cyber Resilience Expanding Our Footprint: Local Cloud Availability for Prisma AIRS in Japan The Invisible CEO of Crisis: Breaking the Cycle of CISO Burnout Securing the Agentic AI Frontier: Palo Alto Networks and Databricks Deliver a New Standard for AI Security Securing Canada’s Digital Future: Why PBMM Matters Beyond Government Beyond Human Oversight: Adapting to the Frontier AI Era Shifting from Data Hoarding to Active Defense: Navigating the New Era of OMB M-26-14 European Digital Sovereignty Starts With Trust How AI and Evasion Demand a Radical Shift in Network Threat Prevention Reinventing Security for the Agentic NVIDIA AI Factory A 4X Gartner Magic Quadrant for EPP Leader. Built for the Agentic Era. Securing and Governing AI Agents At Scale Through A Unified AI Gateway The “Why” Behind NextWave’s New Requirements Beyond the Frontier — Expanding the Ecosystem for Autonomous Defense Defender's Guide to the Frontier AI Impact on Cybersecurity: May 2026 Update From WarGames to Cyberwar Idira — Our Journey to Democratize Privilege Controls A New Era of Security: Frontier AI Defense Nutanix and Palo Alto Networks Integrate for Robust Model Trust 39 Seconds — That's How Long It Takes to Lose Your Data The Dangerous Momentum of Autodownload Phishing Enhancing AI-Driven Defense with Anthropic’s Claude Opus 4.7 Unit 42 Expands Frontier AI Defense with Armadin Partnership Palo Alto Networks and Google Cloud Scaling AI Agents with Confidence Palo Alto Networks Joins DNS-OARC as a Platinum Member The AI Ecosystem Edge — Introducing Our Frontier AI Alliance Defender's Guide to the Frontier AI Impact on Cybersecurity Introducing Unit 42 Frontier AI Defense Securing the UK’s Digital Future Announcing ADEM Universal Agent Closing the Gap by Enhancing Visibility and Mitigating Risks Five Browser and AI Security Questions Keeping CxOs up at Night Securing the Era of Agentic AI with Prisma SASE The Cryptographic Reset Has Begun Prisma Browser for Business — A Secure Workspace for Small Business Securing the Enterprise AI Ecosystem with ServiceNow and Prisma AIRS How NextWave’s Evolution Drives Shared Success Announcing Prisma AIRS Availability in Singapore Region How the National Cyber Strategy Secures Our Digital Way of Life
Palo Alto Networks at Nutanix .NEXT 2026
Lee Space · 2026-04-08 · via Palo Alto Networks Blog

Securing the AI-Powered Hybrid Multicloud

At the core of every modern enterprise is a fundamental need: The ability to innovate across hybrid environments without sacrificing security. For over five years, Palo Alto Networks and Nutanix have partnered to meet this need, building a collaborative ecosystem where industry-leading infrastructure meets the world’s most comprehensive AI-powered security.

As we look toward the future of the enterprise at Nutanix .NEXT 2026, our focus remains on a shared vision for the "Secure Nutanix Cloud."

2026 Global Security Partner of the Year

We are deeply honored to be named the Nutanix 2026 Global Security Partner of the Year. This recognition reflects our commitment to delivering integrated, automated security that feels like a native part of the Nutanix experience. Together, we have helped thousands of joint customers move from reactive security to a proactive, zero trust posture that spans the data center, the edge and the public cloud.

The Existing Partnership Is the Foundation of Trust

Our partnership is built on the belief that security should be invisible, automated and inseparable from the infrastructure it protects. We’ve worked alongside Nutanix to enable enterprises to scale their hybrid multicloud, and their security posture scales with it. Current integrations provide zero trust protection across the Nutanix environment:

  • VM-Series Virtual Firewalls – Seamlessly integrated with Nutanix AHV and Flow Network Security, our virtual firewalls provide Layer 7 visibility and advanced threat prevention for east-west traffic. This integration leverages Nutanix Flow service chaining to automatically steer traffic through VM-Series firewalls for deep packet inspection without manual reconfiguration. It delivers full functional parity and operational continuity for Nutanix AHV environments, allowing security teams to maintain high-performance standards using familiar Panorama® management and persistent, tag-based policies that migrate with workloads across clusters.
  • Hybrid Cloud Security – We provide consistent security for Nutanix Cloud Clusters (NC2) on both AWS and Azure, enabling your policies to follow your workloads wherever they reside.
  • Automation & Orchestration – Leveraging the Panorama® plugin for Nutanix, teams can automate security provisioning and use Dynamic Address Groups to sync application attributes instantly.

New Integration Secures Nutanix Enterprise AI (NAI)

Building on this foundation, the highlight of this year’s show is our groundbreaking integration designed to accelerate Enterprise AI adoption. NAI provides a simplified, cloud-native stack that allows organizations to deploy and scale large language models (LLMs) across their choice of infrastructure with push-button simplicity. We are collaborating on a first-of-its-kind, end-to-end security solution for NAI.

This integration, launching soon, will bring AI Model Security and AI Red Teaming directly into the NAI, creating a seamless experience where security is built in, not bolted on. By allowing only Prisma AIRS™ validated models to reach production, we eliminate security friction at the start of the AI lifecycle. Every model will undergo rigorous scans for known vulnerabilities before deployment, providing a "clean room" environment for AI development. Providing a proactive test of AI defenses, Prisma AIRS AI Red Teaming will be available within NAI as an autonomous solution that integrates seamlessly into the development pipeline, utilizing a combination of a profiler and an attacker agent to perform contextual iterative simulations that mirror real-world attacker behavior. By providing detailed reports that map vulnerabilities directly to the OWASP Top 10 for LLMs and NIST AI RMF, it equips teams with the precise context needed to secure AI applications continuously and effectively.

By proactively identifying and neutralizing emerging threats, we will give organizations the confidence to deploy AI bravely, knowing their innovation is anchored in the world’s most robust security platform.

Powered by Prisma AIRS, this integration will bring a "security-first" approach to your AI deployments:

  • AI Model Security – Scans AI models during the download phase to block malicious code and hidden backdoors before they reach your environment.
  • AI Red Teaming – Provides continuous, autonomous vulnerability hunting on models, application and agent endpoints, testing your AI behavior against more than 750 real-world attack scenarios and contextual agentic risk assessment.
  • Unified Visibility – Provides a complete overview of your AI risk posture and scan summaries directly within your NAI dashboards.

Screenshot of Nutanix Enterprise AI dashboard.

Unified Security Dashboard with AI Model Security and AI Red Teaming

Benefits:

Seamless and Frictionless Deployment

We will prioritize a fast and frictionless deployment experience, ensuring that robust AI security does not come at the cost of development speed. By integrating these controls directly into the NAI workflow, organizations will be able to deploy and scale their AI initiatives with "push-button" simplicity, removing the traditional complexity and friction associated with securing large language models.

Proactive Protection Against Emerging Threats

Leveraging our deep expertise in threat prevention, this solution will proactively identify and block vulnerable or malicious models before they can impact the enterprise environment. By scanning models for hidden backdoors and malicious code during the initial download phase, we will stop threats at the perimeter, allowing only validated, secure models to ever reach your production environment.

A Comprehensive Enterprise Cloud AI Solution

This integration will deliver a comprehensive enterprise cloud AI solution, merging Nutanix’s industry-leading infrastructure with our next-generation security controls. The result will be a unified, cloud-native stack where security is built in rather than bolted on after the workload deployment, providing a secured deployment environment, which is consistent across the data center, the edge and public cloud.

Evolving Insights and Real-Time Remediation

The vulnerability insights from AI Red Teaming are coupled with remediation insights. The platform will provide a prioritized list of remediation steps that are tailor-made for the endpoint. This allows organizations to battle-test their inference endpoints before deploying them at scale.

Key Takeaways

  • A Proven, Award-Winning Partnership: Celebrating five years of collaboration, Palo Alto Networks has been named the Nutanix 2026 Global Security Partner of the Year, highlighting a shared commitment to delivering native, automated zero trust security for hybrid multicloud environments.
  • Seamless Zero Trust for Hybrid Workloads: Through deep integrations with VM-Series virtual firewalls and Nutanix Cloud Clusters (NC2), organizations can maintain consistent Layer 7 visibility and tag-based security policies that automatically follow workloads across on-premises data centers and public clouds.
  • Securing the AI Lifecycle with Prisma AIRS: The new integration with NAI, launching soon, will bring a security-first approach to AI adoption, utilizing Prisma AIRS to scan LLMs for vulnerabilities during download, and perform autonomous Red Teaming to neutralize emerging threats before they reach production.

Don’t Miss Our Speaking Session

Want to see the integration in action? Join our experts, Shrikant Brahmbhatt (Palo Alto Networks) and Ashwini Vasanth (Nutanix), on Tuesday April 7 3:30-4pm for an exclusive look at how we are securing the "Challenge of Hybrid AI." We’ll dive into the architecture that allows you to discover, assess and protect your entire AI ecosystem (apps, agents and models alike).

Visit Us at Booth #G2

Stop by the Palo Alto Networks booth (#G2) to meet our team of over 19,000 active threat researchers and see live demos of our joint solutions. Whether you are building the next generation of agentic AI or securing your virtual desktop infrastructure (VDI), we have the tools to help you innovate at machine speed.

Ready to secure your journey? Visit the Palo Alto Networks partner directory or learn more about Prisma AIRS.

Forward-Looking Statements

This blog contains forward-looking statements that involve risks, uncertainties and assumptions, including, without limitation, statements regarding the benefits, impact, or performance or potential benefits, impact or performance of our products and technologies or future products and technologies. These forward-looking statements are not guarantees of future performance, and there are a significant number of factors that could cause actual results to differ materially from statements made in this blog, including, without limitation: developments and changes in general market, political, economic, and business conditions; risks associated with managing our growth; risks associated with new products and subscription and support offerings; shifts in priorities or delays in the development or release of new offerings, or the failure to timely develop, release and achieve market acceptance of new products and subscriptions as well as existing products and subscription and support offerings; failure of our business strategies; rapidly evolving technological developments in the market for security products and subscription and support offerings; our customers’ purchasing decisions and the length of sales cycles; our competition; our ability to attract and retain new customers; and our ability to acquire and integrate other companies, products, or technologies. We identify certain important risks and uncertainties that could affect our results and performance in our most recent Annual Report on Form 10-K, our most recent Quarterly Report on Form 10-Q, and our other filings with the U.S. Securities and Exchange Commission from time-to-time, each of which are available on our website at investors.paloaltonetworks.com and on the SEC's website at www.sec.gov. All forward-looking statements in this blog are based on information available to us as of the date hereof, and we do not assume any obligation to update the forward-looking statements provided to reflect events that occur or circumstances that exist after the date on which they were made.