High estrogen in the brain's memory center may worsen one's resilience against traumatic events, swaying the tendency to develop memory problems or post-traumatic stress in the aftermath, a recent study in mice suggests.

The research, published in April in the journal Neuron, explored the effects of estrogen in the mouse brain. It zoomed in on the hippocampus, a key part of the brain involved in learning and memory. Both male and female mammals produce significant amounts of estrogen in the hippocampus, despite it often being framed as a "female" hormone.