Frameproof codes are a class of secure codes that were originally introduced in the pioneering work of Boneh and Shaw in the context of digital fingerprinting. They can be used to enhance the security and credibility of digital content. Let $M_{c,l}(q)$ denote the largest cardinality of a $q$-ary $c$-frameproof code with length $l$. Based on an intriguing observation that relates $M_{c,l}(q)$ to the renowned Erdős Matching Conjecture in extremal set theory, in 2003, Blackburn posed an open problem on the precise value of the limit $R_{c,l}=\lim_{q\rightarrow\infty}\frac{M_{c,l}(q)}{q^{\lceil l/c \rceil}}$. By combining several ideas from the probabilistic method, we present a lower bound for $M_{c,l}(q)$, which, together with an upper bound of Blackburn, completely determines $R_{c,l}$ for {\it all} fixed $c,l$, and resolves the above open problem in the full generality. We also present an improved upper bound for $M_{c,l}(q)$.