This paper considers a network of infinite-server queues with the special feature that, triggered by specific events, the network population vector may undergo a linear transformation (a `multiplicative transition'). For this model we characterize the joint probability generating function in terms of a system of partial differential equations; this system enables the evaluation of (transient as well as stationary) moments. We show that several relevant systems fit in the framework developed, such as networks of retrial queues, networks in which jobs can be rerouted when links fail, and storage systems. Numerical examples illustrate how our results can be used to support design problems.