In this paper, we prove two conjectures of Z.-W. Sun: $$2n\binom{2n}n\big|\sum_{k=0}^{n-1}(3k+1)\binom{2k}k^3{16}^{n-1-k}\ \mbox{for}\ \mbox{all}\ n=2,3,\cdots,$$ and $$\sum_{k=0}^{(p-1)/2}\frac{3k+1}{16^k}\binom{2k}{k}^3\equiv p+2\left(\frac{-1}{p}\right)p^3E_{p-3}\pmod{p^4},$$ where $p>3$ is a prime and $E_0,E_1,E_2,\cdots$ are Euler numbers.