By formulating the floorplanning of VLSI as a mixed-variable optimization problem, this paper proposes to solve it by memetic algorithms, where the discrete orientation variables are addressed by the distribution evolutionary algorithm based on a population of probability model (DEA-PPM), and the continuous coordination variables are optimized by the conjugate sub-gradient algorithm (CSA). Accordingly, the fixed-outline floorplanning algorithm based on CSA and DEA-PPM (FFA-CD) and the floorplanning algorithm with golden section strategy (FA-GSS) are proposed for the floorplanning problems with and without fixed-outline constraint. %FF-CD is committed to optimizing wirelength targets within a fixed profile. FA-GSS uses the Golden Section strategy to optimize both wirelength and area targets. The CSA is used to solve the proposed non-smooth optimization model, and the DEA-PPM is used to explore the module rotation scheme to enhance the flexibility of the algorithm. Numerical experiments on GSRC test circuits show that the proposed algorithms are superior to some celebrated B*-tree based floorplanning algorithms, and are expected to be applied to large-scale floorplanning problems due to their low time complexity.