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Athletics vs. San Diego Padres prediction, pick for MLB on Sunday 5/24/26
Dan Johnson · 2026-05-25 · via DraftKings Network

Dan Johnson takes you through his preview, prediction, and best bet for today’s baseball game between the Athletics and the San Diego Padres.

The Athletics and Padres close their weekend series at Petco Park with San Diego chasing a sweep and Oakland trying to drag one game back before leaving town. The Padres enter 31-20 after taking the first two games 7-3 and 2-0, while the Athletics sit 26-26 after an offense that had just scored 14, six and three runs in its previous three wins was held quiet in San Diego. Saturday’s game captured the texture of the series: the Padres scored on a bases-loaded hit-by-pitch and an RBI groundout, went 0-for-5 with runners in scoring position, and leaned on Ty France’s defense to turn multiple double plays. Petco Park is sitting in a low-clouds-to-sunshine pocket around the mid-to-upper 60s, with no rain issue and no obvious carry boost, which gives the finale the same narrow-margin feel as the first two games. Below is my preview, prediction, and pick for today’s baseball game between the Athletics and the San Diego Padres.

Here’s how I’ll play it. I’ll be pumping out these predictions for individual games all season, with plenty of coverage here on DraftKings Network. Follow my handle @dansby_edits for more betting plays.

Athletics vs. Padres prediction, preview

Michael King is the reason San Diego is priced like a heavy favorite. He enters 4-2 with a 2.31 ERA, 1.06 WHIP, 59 strikeouts, 24 walks, four HR allowed and only 38 hits surrendered in 58.1 innings, and the contact suppression is strong enough to support the run environment: 86.5 mph average exit velocity allowed, 31.9% hard-hit rate, .268 wOBA, .302 xwOBA and 9.2% barrel rate. His last start was the ideal Padres version of this game—seven scoreless innings, four hits, two walks and nine strikeouts in a 1-0 win over the Dodgers. Oakland’s side is less straightforward because Luis Medina’s 1-1 record, 2.41 ERA, 1.18 WHIP, 18 strikeouts, nine walks, one HR and 13 hits allowed in 18.2 innings likely comes in an opener/bulk structure with Jacob Lopez behind him. Medina’s contact profile is more volatile than the ERA, with 91.6 mph average exit velocity allowed, 39.2% hard-hit rate, 10.0% barrel rate, .261 wOBA and .338 xwOBA, but the structure can still keep San Diego from getting a single clean starter look.

Oakland has too many legitimate bats to make Padres ML -181 comfortable. The A’s have hit .251 with a .742 OPS vs. right-handed pitching, and Carlos Cortes gives the top of the order a real contact-and-counts piece, batting .327 vs. righties while carrying a season profile with 34 hits in 99 at-bats, four HR, nine walks, only 10 strikeouts, an 89.9% contact rate and a .213 ISO. Nick Kurtz is the bigger on-base and damage problem with a 46-game on-base streak, a .281/.443/.489/.932 season line, eight HR, 37 RBI, 50 walks, plus a 94.6 mph average exit velocity, 58.3% hard-hit rate, 16.5% barrel rate, 40.0% sweet-spot rate, .410 wOBA and .393 xwOBA. Shea Langeliers adds the loudest catcher power on the card, with 12 HR, 56 hits in 166 at-bats, a .277 ISO, 49.4% fly-ball rate, 50.6% ground-ball rate, 15.5% barrel rate, .421 wOBA and .408 xwOBA. Zack Gelof brings lower-order thump and speed with six HR, 17 RBI, six steals, a .458 SLG, .747 OPS, .246 ISO and 42.9% fly-ball rate, while Tyler Soderstrom has five HR, 18 walks, a .190 ISO and 46.2% fly-ball rate. Brent Rooker’s average has lagged, but seven HR, 25 RBI, 15 walks, a .164 ISO and a 14.8% barrel rate still give Oakland another mistake-punishment bat before Jeff McNeil’s .277/.341/.374 contact profile stretches the order.

San Diego’s lineup has recognizable names, but the production is still priced more like reputation than current form. Fernando Tatis Jr. has recently been better against righties, hitting .357/.471/.357 over his last five games vs. RHP, and his underlying contact remains healthier than the slugging line with 90.9 mph average exit velocity, 54.3% hard-hit rate, 10.7% barrel rate and .388 xSLG, but the season line is still only .238/.319/.276 with zero HR. Gavin Sheets is the cleanest Padres damage bat, carrying nine HR, 10 doubles, 23 RBI, a .254/.335/.522/.857 slash, a .294 ISO, 89.2 mph average exit velocity, 43.8% hard-hit rate, 10.1% barrel rate, .374 wOBA and .356 xwOBA. Miguel Andújar has been productive enough to matter with five HR, a .281/.305/.486 line, .205 ISO, .342 wOBA and two homers over his last five games vs. righties, while Ty France has added four HR, a .278/.305/.519/.824 slash and a 14.1% barrel rate in a smaller role. The concern is the core around them: Manny Machado is at .176/.271/.341 with eight HR, 43.9% hard-hit rate and a 6.8% barrel rate; Xander Bogaerts sits around .243/.311/.379 with seven HR; Jackson Merrill is at .206/.278/.328 with four HR, a 9.2% barrel rate and a 25.0% strikeout rate; Ramón Laureano’s 14.2% barrel rate is real, but the .217/.297/.385 line keeps the order streaky. San Diego can win with one swing and pitching, but the lineup is still more scratch-and-survive than sustained pressure.

Padres vs. Athletics pick, best bet

The market is asking for too much faith in San Diego’s offense. Padres ML -181 leans heavily on King, and Padres -1.5 +123 asks a low-total lineup to create margin in a park that turns plenty of solid contact into long outs. Athletics +1.5 around -149 makes sense because Oakland has a better righty-split offense than the price implies, but that juice is ugly for a road dog facing the best pitcher in the game. F5 under 4.5 at -130 is strong because King can control the first turn and the Medina/Lopez setup can keep San Diego guessing, yet the full-game under 7.5 at -110 gets the better number while still leaning into Petco, King’s length and the Padres’ offensive drag. Padres team total under 4.5 at -145 is pointed the right direction with too much tax. The full-game total is the cleanest menu item because both offenses have reasons to threaten without carrying enough reliable paths to stack four or five scoring innings.

Best bet: Under 7.5 -110. Playable to -115. The failure path is Oakland’s top half forcing King into pitch-count stress through Cortes, Kurtz and Langeliers while Sheets or Andújar turns San Diego’s side of the Medina/Lopez game into a multi-run inning. The stronger baseline is a controlled Petco game: King limits the loudest A’s contact, San Diego scores through pockets rather than waves, and both teams spend the afternoon looking for one clean rally instead of stacking them.

Final score: Padres 4, Athletics 2.

Best bet: Athletics vs. Padres u7.5 total runs (-110)

Tail it with me in the DKN Betting Group here!