Tru Niagen Beauty is Niagen Bioscience's newest foray into inside out wellness.

Courtesy of Tru Niagen

Tru Niagen is expanding its patented nicotinamide riboside, known as Niagen, into skincare and beauty supplements. Driven by consumer demand, Niagen Bioscience’s leadership in NAD+ skincare science with a cellular-first formula designed to support skin elasticity and the appearance of hair, skin, and nails. As consumers have built trust with the efficacy of Tru Niagen and are looking to integrate more NAD+ products into their routines, especially with skincare products and supplements.

One capsule of Tru Niagen Beauty delivers 100 mg of Niagen, combining NAD+ support with a precision blend of clinically studied ingredients known to nourish beauty from within. The blend features Astaxanthin, which supports smooth, hydrated skin and provides antioxidant support, Hyaluronic Acid, which helps support skin hydration and elasticity as you age, Grape Seed Extract, which offers antioxidant support to help maintain an even skin tone, Biotin, which supports healthy hair, skin, and nails, and Vitamin E which helps protect against oxidative stress to support the skin’s natural resilience. “Healthy, resilient skin starts below the surface,” said Tiffany Libby, MD, Double Board-Certified Dermatologist, Mohs Surgeon at Brown Dermatology in Rhode Island. “Tru Niagen Beauty represents a new chapter in NAD+ skincare science—supporting the cellular foundation for healthy, radiant skin.”

With science at the foundation of Niagen, consumer products are still the main driver of growth for the brand. In 2025, total net sales increased 30% to $129.4 million, with Tru Niagen sales of $97.7 million and Niagen ingredient sales of $27.9 million, up 27% and 45%. Just in Q4 of 2025 alone, total net sales increased 16% to $33.8 million, with Tru Niagen sales of $27.5 million, up 21% from the prior year quarter. “Science drives everything we do. We’re not chasing trends, we’re building the foundation for better aging. Every product is rooted in rigorous R&D, grounded in the biology of NAD+, and backed by data that shows real impact on human health,” Michiko Kelley, CMO of Niagen Bioscience, explained. “We have a unique External Research Program that, to our knowledge, is unlike anything else in the industry. Through this program, independent investigators worldwide from institutions such as MIT, NIH, Harvard, and Cambridge come to us requesting our patented nicotinamide riboside ingredient, Niagen, for their preclinical and clinical research on NAD+. There are 300+ research collaborations and 46 peer-reviewed published clinical studies on Niagen to date. Importantly, due to the unique nature of the program, over 90% of the published clinical research on Niagen is conducted independently (meaning we do not have a say in study design or outcomes).”

On their skincare product, Niagen NanoCloud is a waterless NAD+ formula you activate yourself. It is fresh, potent, and designed to deliver results your skin can actually feel. Niagen NanoCloud is the first product from Niagen’s newly launched Skincare Innovation Lab, a space dedicated to turning NAD+ science from Tru Niagen supplements into skincare. NAD+ helps repair, regenerate, and energize your skin for smoother texture, better hydration, and a radiant, youthful glow. Since NAD+ precursors break down in water, this precision-delivery format keeps Niagen, the patented form of NR, stable until the moment it touches your skin. The formula also includes sodium hyaluronate, pullulan, squalene and Vitamin E.

“Niagen has changed how the world thinks about cellular health,” said Rob Fried, CEO of Niagen Bioscience. “Our customers do not want trends; they want proof. Tru Niagen Beauty builds on years of trust in Tru Niagen, delivering a daily, stackable product to care for skin, hair, and nails at the cellular level.

As NAD+ has become increasingly recognized as fundamental to cellular health, scientific interest in effective NAD+ augmentation continues to grow. Through Niagen’s external research program, investigators worldwide are turning to Niagen as the trusted NAD+ booster for rigorous, independent research, and we are proud to support both established and next-generation scientists exploring its potential across aging and disease. “Since its founding nearly thirteen years ago, our external research program has advanced the science of Niagen and evolved into a unique, industry-leading platform for independent NAD+ research. Third-party investigators from leading institutions worldwide, including the National Institutes of Health (NIH), Mayo Clinic, Harvard University, and Cambridge University, have requested Niagen for clinical and preclinical research because Niagen Bioscience is a trusted partner and Niagen is the most efficient and effective high-quality NAD+ booster available,” shared Yasmeen Nkrumah-Elie, PhD, Global Director of External Research.

Nkrumah-Elie also shared that a randomized, double-blind, placebo-controlled clinical trial with healthy adults, 1,000 mg of Tru Niagen, led to an average 150% increase in NAD+ levels after just three weeks. As it goes for skin health, Han et al. (2023) demonstrated that elevating NAD+ with Niagen reduced inflammatory signaling in healthy subjects and immune cells derived from psoriasis patients, contributing to what has now grown to 7 clinical studies demonstrating the anti-inflammatory benefits of Niagen in both healthy and disease populations. “We’re hopeful that we’ll continue expanding into new institutions, geographies, therapeutic areas, and delivery modalities as interest in NAD+ biology grows and researchers seek to better understand the role of Niagen in health, resilience, and aging. We also expect to expand the program into new areas of investigation, including topical applications, intravenous and injectable administration with pharmaceutical-grade Niagen, and the evaluation of additional novel NAD+ precursors,” she added.

Niagen Bioscience also offers Niagen Plus^™, featuring pharmaceutical-grade intravenous (IV) and injectable Niagen products. Going forward Niagen is exploring future NAD+ skincare innovation and wellness from the inside out.