What did Franklin D. Roosevelt and Winston Churchill have in common, besides shaping mid‑20th mid‑20th‑century history? Both suffered from hypertension, a condition Western medicine did not recognise as a disease until well into the 1940s. High blood pressure was seen as an inevitable companion of aging, something to be endured rather than treated. Doctors advised lifestyle changes, less salt, more rest, and, at best, mild sedatives.

Long before this shift in medical thinking, Indian practitioners were using the roots of Sarpagandha to treat manic disorders. Drawing on this traditional knowledge, Ram Nath Chopra, the father of Indian pharmacology, demonstrated that the herb could also bring down blood pressure. His work marked a turning point. Building on Chopra’s research and clinical trials by Indian doctors, the Swiss pharmaceutical company Ciba isolated the active alkaloid responsible for Sarpagandha’s hypotensive effect. The result was Reserpine, the world’s first effective drug to control hypertension.