The wide-ranging prosecution in the death of “Friends” star Matthew Perry is coming to a close. Five people have pleaded guilty for various roles in supplying the actor with ketamine, the drug that killed him at age 54 in 2023. Three of them have been sentenced. The last two will be sentenced in the coming days.

Here's a look at each person.

Mr. Perry’s 60-year-old longtime live-in personal assistant Mr. Kenneth Iwamasa was intimately involved in the actor’s illegal ketamine use, acting as his drug messenger and personally giving him injections — six to eight per day in the last days of his life — according to his plea agreement.

“Shoot me up with a big one,” Mr. Iwamasa told authorities Mr. Perry said to him on Monday (May 11, 2026). After several injections, the assistant left him at his home in the Pacific Palisades neighborhood of Los Angeles and returned to find Mr. Perry dead in his hot tub. An autopsy found the primary cause of death was the acute effects of ketamine, with drowning as a secondary cause.

Mr. Iwamasa made nearly all of the illegal drug buys on Perry’s behalf, working in coordination with his co-defendants. One of them, Dr. Salvador Plasencia, taught him how to give Mr. Perry the injections.

Mr. Iwamasa was quick to participate with police and prosecutors, becoming the first to reach a plea deal as they sought to use him as a key witness against other defendants.

PLEADED GUILTY TO: One count of conspiracy to distribute ketamine causing death.

SENTENCE: He’s scheduled to become the final defendant sentenced on Wednesday (May 13, 2026)

WHAT THEY SAID: Mr. Iwamasa is the only defendant who has yet to give public comment.

Prosecutors say she was known as “The Ketamine Queen,” because of her jet-setting, drug dealing lifestyle. Her lawyers say authorities made up that nickname to feed a media frenzy.

Ms. Jasveen Sangha did admit to running a serious drug operation, selling Mr. Perry the dose of ketamine that he took on the day he died, and causing the death of another man, 33-year-old Mr. Cody McLaury, in 2019.

Like the other defendants, Ms. Sangha had no previous convictions.

But, prosecutors said, and a judge agreed, that unlike the other defendants whose actions were atypical, she had been dealing drugs including ketamine, methamphetamine and cocaine for at least five years from her home.

Ms. Sangha is a 42-year-old who was born in Britain, raised in the United States and has dual citizenship. Her social media accounts showed her in posh spaces alongside rich-and-famous faces in Spain, Japan and Dubai, London and Los Angeles.

Ms. Sangha went to high school in Calabasas, California — perhaps best known as home to the Kardashians — and went to college at the University of California, Irvine, graduating in 2005 and going to work at Merrill Lynch. She later got an MBA from the Hult International Business School in London.

Her lawyers presented that personal history as evidence that she was an otherwise upstanding citizen, but prosecutors used the same facts to argue she didn't need to sell drugs but did so for greed and glamour.

PLEADED GUILTY TO: Three counts of distribution of ketamine, one count of distribution of ketamine resulting in death or serious bodily injury, and one count of using her home for drug distribution.

SENTENCE: She was sentenced to 15 years in prison, the longest so far.

WHAT THEY SAID: “These were not mistakes. They were horrible decisions,” Ms. Sangha said at sentencing, adding that her choices had “shattered people’s lives and the lives of their family and friends.”

Erik Fleming, 56, was working as a drug addiction counselor when a mutual friend he had with Mr. Perry told him that the actor was seeking ketamine, according to filings from prosecutors.

Mr. Fleming’s lawyers said he was a former television and film producer whose career had been ravaged by substance abuse, and that after gaining hard-won sobriety he became a counselor.

But he had badly relapsed when approached about Mr. Perry, and connected the actor with Ms. Sangha to buy her product.

In all, prosecutors say, Mr. Fleming delivered 50 vials of Ms. Sangha’s ketamine for Mr. Perry’s use, marking up the price to make a profit, including 25 vials sold for $6,000 to the actor four days before his death.

Authorities found him early in the investigation and lawyers on both sides agreed he was immediately and extraordinarily cooperative. He gave up Ms. Sangha, and became the first to appear in court and enter a guilty plea.

PLEADED GUILTY TO: One count of distribution of ketamine resulting in death.

SENTENCING: He is scheduled to be sentenced Wednesday (May 13, 2026). Prosecutors have asked for 2 1/2 years in prison. The defense has asked for three months followed by nine months in a residential treatment program.

WHAT THEY SAID: “I procured ketamine for Mr. Perry because I wanted the money and because I thought I was doing a favor for a friend,” Mr. Fleming wrote in a presentencing letter to the court. “I never contemplated the worst possible outcome. This grievous failure will haunt me forever.”

“I wonder how much this moron will pay?”

That was a text message Dr. Salvador Plasencia sent to a fellow doctor when he learned Mr. Perry was looking for illegal, off-the-books ketamine, according to a plea agreement where the doctor admitted to selling 20 vials of the drug to the actor in the weeks before his death.

Mr. Plasencia, a 44-year-old Los Angeles-area doctor known to patients as “Dr. P,” was one of the main targets of the prosecution and had been headed for a joint trial with Sangha when he reached the plea agreement last year.

Mr. Perry was connected to Dr. Plasencia through another patient. The actor had been getting ketamine legally from his regular doctor as treatment for depression, an off-label but increasingly common use of the surgical anesthetic. But he wanted more than that doctor would prescribe.

Dr. Plasencia admitted to injecting Perry with some of the initial vials he provided, and left more for Mr. Iwamasa to inject, despite the fact that Perry froze up and his blood pressure spiked after a dose.

Dr. Plasencia graduated from UCLA's medical school in 2010 and had not been subject to any medical disciplinary actions before the Perry case.

PLEADED GUILTY TO: Four counts of distribution of ketamine.

SENTENCE: 2 1/2 years in prison, two years of probation and a $5,600 fine.

WHAT THEY SAID: Dr. Plasencia cried at his sentencing as he imagined the day he would have to tell his 2-year-old son “about the time I didn’t protect another mother’s son. It hurts me so much.”

Mr. Mark Chavez, a San Diego doctor who ran a ketamine clinic, was the source of the doses that Dr. Plasencia sold to Mr. Perry.

Dr. Chavez admitted to obtaining the ketamine from a wholesale distributor on false pretenses and passing it along.

Dr. Chavez, 55, graduated from UCLA's medical school in 2004 and he has surrendered his medical license.

CHARGE: One count of conspiracy to distribute ketamine.

SENTENCING: Eight months of home confinement and three years of supervised release.

WHAT THEY SAID: “I just want to say my heart goes out to the Mr. Perry family,” Dr. Chavez said at sentencing.