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Proofpoint Expands AI-Powered Investigations to Microsoft 365 and Deepens Insider Risk Visibility into AI Activity | Proofpoint US Four groups caught using the same Chrome and Windows exploit kit CISOs are feeling the security burden of accelerated AI use Chinese espionage groups swarm to exploit triple-link chain of zero-days Proofpoint 2026 Voice of the CISO Report Finds Cyber Resilience Improving, While AI Expands the CISO Mandate | Proofpoint US Proofpoint SOC Analyst Agent Uses OpenAI Cyber Models Proofpoint Strengthens Executive Leadership Team with Appointment of Chief Legal Officer and Chief People Officer | Proofpoint US Proofpoint Brings OpenAI GPT Cyber Models into Security Operations to Help Defenders Investigate Threats Faster | Proofpoint US Cybercriminals Turn to Indirect Prompt Injection Attacks Fox News Proofpoint Joins Google Unified Security Recommended Program to Help Organizations Defend Against Today’s Most Sophisticated Threats | Proofpoint US Proofpoint Launches OEM Program to Help Security Providers Embed Trusted Threat Intelligence and Detection Capabilities | Proofpoint US Max-severity Exchange server flaw under active exploitation by Kremlin hackers New warnings that Russian operatives are targeting the emails of US nuclear scientists and defense contractors | CNN Politics International alert spotlights Russia-linked attacks on Zimbra webmail US and allies say Russian hackers stole emails without social engineering If you pay a hacker's ransom, chances are that they'll come back for more | TechCrunch Proofpoint Research Finds 65% of Organizations Affected by Ransomware Say AI Made Attacks More Effective | Proofpoint US The Hacker News Hackers find a new trick to collect Microsoft Entra user data without raising red flags Suspected Chinese snoops caught breaking into universities New Cargo Theft Surge: From Lobster Heists To Bourbon Warehouse Scams Defending the Authentication Flow: Device Code Phishing with Selena Larson Proofpoint Joins the OpenAI Daybreak Cyber Partner Program to Advance Responsible AI-Powered Cyber Defense | Proofpoint US OpenAI Lets Cyber Vendors Embed GPT-5.5 in Defenses Suspected North Korean actors use fake ‘coding assignments’ to steal crypto China-Linked TA4922 Expands Phishing Attacks to U.K., Germany, Italy, and South Africa Proofpoint Introduces Active Exploits Protection to Help Organizations Prioritize Vulnerability Patching for Real-World Attacks in the AI Era | Proofpoint US Verizon DBIR: Healthcare Fends Off Increased Social Engineering Attacks Proofpoint Launches Dedicated MSP Business Unit and Introduces 365 Total Protection for North America | Proofpoint US
Proofpoint Integrates with the Claude Compliance API to E...
2026-05-20 · via Proofpoint News Feed

New product integrations bring data protection, insider risk detection, and governance into Claude Enterprise and Claude Platform activity 

  • Organizations gain unified visibility across AI prompts, responses, files, activity logs, and workflows.  
  • Customers can extend existing data loss, behavioral risk, and supervision controls into Claude without deploying a separate AI security stack.  
  • One control layer governs human and AI activity across endpoint, cloud, email, collaboration tools, and AI applications, including Claude. 

SUNNYVALE, Calif., May 21, 2026 — Proofpoint, Inc., a leading cybersecurity and compliance company, today announced the integration of Proofpoint’s platform with the Claude Compliance API. The integration extends Proofpoint’s data security, data loss prevention (DLP), insider risk, AI runtime security, and Digital Communications Governance (DCG) directly into Claude, enabling enterprises to apply the same controls they use across endpoint, email, and cloud to AI-assisted work. 

AI agents are now operating inside organizational workflows with access to sensitive data, collaboration tools, and systems once limited to people. According to Proofpoint's 2026 AI and Human Risk Landscape Report, nearly nine in ten global organizations have moved AI assistants beyond pilot, yet 42% have already experienced a suspicious or confirmed AI-related incident.  

Security programs built around human activity need to evolve and extend to also include AI activity to get a complete view of risk. As organizations deploy Claude at scale, AI agents are reading files, drafting communications, influencing decisions, and triggering workflows. That activity must be visible, governed, and defensible within existing security and compliance frameworks as opposed to being managed through separate AI-specific stacks. 

“Organizations cannot succeed with one governance model for people and another for AI,” said Mayank Choudhary, EVP and GM of Proofpoint’s Information Protection, Cloud Security, and Compliance Products Group. “Humans and AI agents operate in the same workflows, access the same sensitive data, and shape the same business decisions. They require one control layer. By extending our data security, insider risk, and communications governance solutions into Claude, we’re enabling customers to manage AI activity through the same platform they trust to protect the rest of their enterprise. We are excited to integrate with the Claude Compliance API, which makes the integration of controls secure and scalable.” 

Extending Data Security and Insider Risk for AI 

The first integration brings Claude Enterprise conversation content and Claude Platform activity logs into Proofpoint’s data security and insider risk solution. 

Enterprises can apply existing classifiers, behavioral risk models, and data loss prevention policies to Claude Enterprise prompts, responses, files, projects, and administrative activity, while monitoring activity logs from Claude Platform. AI interactions are evaluated using the same detection logic that protects endpoint, cloud, and email environments. 

This allows organizations to enforce consistent data controls, detect anomalous behavior across human and AI activity, and investigate AI-assisted workflows within the same risk framework already deployed across the enterprise without introducing a separate AI security stack. 

Bringing Digital Communications Governance into the AI Workflow 

The second integration extends Proofpoint’s Digital Communications Governance (DCG) into Claude Enterprise. 

Capturing transcripts alone is not sufficient for regulatory supervision or investigations. Enterprises must understand context, intent, and the sequence of activity behind decisions. By bringing Claude conversations into Proofpoint’s solution, organizations can apply supervision, retention, eDiscovery, and investigation workflows to AI-assisted communications. The integrated solution analyzes communication patterns to extract meaning beyond raw content, enabling defensible review and decision reconstruction across both human- and AI-generated interactions. 

Availability 

The integrations with the Claude Compliance API are available today for all Proofpoint and Anthropic customers deploying Claude Enterprise and Claude Platform in Anthropic-hosted environments.  

To learn more about Proofpoint’s integration with the Claude Compliance API, visit: https://www.proofpoint.com/us/blog/information-protection/governing-claude-you-govern-your-people-claude-compliance-api 

About Proofpoint, Inc.  

Proofpoint, Inc. is a global leader in human- and agent-centric cybersecurity, securing how people, data and AI agents connect across email, cloud and collaboration tools. Proofpoint is a trusted partner to over 80 of the Fortune 100, over 10,000 large enterprises, and millions of smaller organizations in stopping threats, preventing data loss, and building resilience across people and AI workflows. Proofpoint’s collaboration and data security platform helps organizations of all sizes protect and empower their people while embracing AI securely and confidently. Learn more at www.proofpoint.com.  

  
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Proofpoint is a registered trademark or tradename of Proofpoint, Inc. in the U.S. and/or other countries. All other trademarks contained herein are the property of their respective owners.