Jason Gerberry
BofA Securities, Research Division

Good day, everybody. We're going to get going here at the BofA Annual Healthcare Conference and our last company presentation with Fractyl Health. My name is Jason Gerberry.

I am -- I cover pharma and biotech here at BofA, and we're joined by Harith Rajagopalan, Co-Founder and CEO; and Lisa Smith Weber (sic) [ Lara Smith Weber ], CFO. So thank you both for joining us here at the conference. Glad to be here. Thanks.

Lara Weber
CFO & Treasurer

Thank you.

Jason Gerberry
BofA Securities, Research Division

So maybe just get things started with a little bit about Revita, your lead program and a little bit of the why, if you will, what you're looking to solve for, how you're looking to improve upon outcomes for individuals with obesity.

Harith Rajagopalan
Co-Founder, CEO & Director

Sure. So Revita is duodenal mucosal resurfacing. It's a catheter-based technology to ablate the duodenal dysfunction that we believe is a root cause of obesity in type 2 diabetes. And our lead indication is what we think to be the largest problem that remains in obesity today, which is how do you achieve durable weight loss maintenance in the absence of ongoing medical therapy.

I think it's pretty obvious that GLP-1s have transformed the treatment landscape and have demonstrated extraordinary weight loss, but most people stop taking these medicines within the first year of therapy. The more weight they lose, the more rapidly they regain their weight and whatever metabolic benefits that they had go away as