惯性聚合 高效追踪和阅读你感兴趣的博客、新闻、科技资讯
阅读原文 在惯性聚合中打开

推荐订阅源

H
Help Net Security
月光博客
月光博客
IT之家
IT之家
B
Blog RSS Feed
T
Tailwind CSS Blog
The GitHub Blog
The GitHub Blog
博客园 - 三生石上(FineUI控件)
MyScale Blog
MyScale Blog
J
Java Code Geeks
Stack Overflow Blog
Stack Overflow Blog
奇客Solidot–传递最新科技情报
奇客Solidot–传递最新科技情报
Cyber Security Advisories - MS-ISAC
Cyber Security Advisories - MS-ISAC
博客园 - Franky
博客园 - 叶小钗
阮一峰的网络日志
阮一峰的网络日志
freeCodeCamp Programming Tutorials: Python, JavaScript, Git & More
U
Unit 42
博客园_首页
B
Blog
V
V2EX
腾讯CDC
Vercel News
Vercel News
量子位
Microsoft Security Blog
Microsoft Security Blog

The Guardian

Rory McIlroy surges into six-shot Masters lead with stunning second-round flourish ‘That’ll be the end’: actor Sam Neill joins fight to stop controversial goldmine near his New Zealand vineyard Roberto De Zerbi targets ‘Ange-ball’ revival to save Spurs from relegation Bath hit back to reach semi-final after stunning Northampton in 11-try epic Secret Garden to Outcome: the week in rave reviews Zebras, wealth and power: Hungary’s election tests Orbán’s grip on power ‘TikTok effect’ brings sellout crowds and younger fans to Grand National meeting The war over Omagh’s gold: the £21bn mine plan tearing a community apart Britain’s shadow workforce is paid as little as 65p an hour. Who cares for the carers? From You, Me & Tuscany to Euphoria: your complete entertainment guide to the week ahead Six great reads: the man who let snakes bite him, masked heavy metal and the brutal reality for foreign students in the UK American Classic review – I defy you not to fall in love with Kevin Kline and Laura Linney’s tender comedy Cuba’s doctors were a lifeline for the world. Now the Caribbean is shamefully complicit in the US drive to expel them An environmental disaster in Moldova has Russia’s fingerprints all over it RMIT drops misconduct case against student who accused university of being ‘complicit in Gaza genocide’ Ichiro Suzuki statue unveiling goes awry as bronze bat snaps during ceremony Survivors of Epstein’s abuse accuse Melania Trump of ‘shifting burden’ on to victims European football: Real Madrid held at home by Girona to extend winless run Arne Slot insists he is ‘aligned’ with Liverpool board and fans as squad is rebuilt Kamala Harris ‘thinking about’ running for president again in 2028 JD Vance warns Iran against trying to ‘play’ the US in peace talks West Ham double up twice to thrash Wolves and put Spurs in relegation zone Trump administration releases new renderings of so-called ‘Arc de Trump’ Crispin Odey drops £79m libel claim against FT over sexual misconduct allegations Bafta apologises for events surrounding John Davidson’s Tourette’s outburst Cocktail of the week: Bar Shrimp’s la rosita – recipe New drug may extend survival in aggressive ovarian cancer, trial shows One dead and 27 injured after bus with British passengers crashes in Canary Islands Pope adds to Smith’s mass of Surrey runs with England woes a world away OpenAI CEO Sam Altman’s home targeted with molotov cocktail
A game-changer for good health? Scientists believe ‘we ar...
Devi Sridhar · 2026-05-05 · via The Guardian

Reduce your calories. Eat more vegetables. Limit soft drinks and junk foods. For years, even decades, this has been the advice for those wanting a healthy body weight, lower blood pressure and better markers of metabolic health. Most weight-loss advice has focused on either what to eat (and what to avoid), or how much to eat. Think of dietary pyramids produced by government agencies, calories on food packaging and meals, and typical nutritional advice.

It’s all true, to a certain extent: it’s obviously better to eat a healthier, nutritionally balanced diet, and yes, lower body weight is broadly linked to reducing calories. But this type of approach can be hard to sustain. Even as a personal trainer who knows what I “should” be eating according to government dietary advice and has heard too much about calorie deficits, I take a slightly different approach to food. I think we need to bring nuance and a balanced approach to food and what we eat.

Sometimes I just want a piece of chocolate cake, although I know a fruit salad would be a nutritionally better choice. Also, counting calories and classifying foods as “good” or “bad” can not only be boring and time-consuming, it can also tip into disordered eating such as orthorexia, described by the British Dietetic Association as a “pathological fixation on healthy eating”. Plus, feeling hungry is hard to sustain over months and years, compared with a limited number of days.

So I was thrilled to read a new study that should have made headlines around the world. This meta-analysis investigates another dietary question: does when you eat make a difference? Researchers analysed 41 randomised controlled trial studies to look at the impact of early or mid-time restricted eating on a number of body weight and blood markers. Around 2,200 participants (42% women) with a mean age range of 19-69 years old were tracked for 4-48 weeks, depending on the study. Early-time restricted eating meant the last meal was eaten before 5pm, while mid-time was a meal ending between 5-7pm and late-time was ending a meal after 7pm.

The findings complicate the “calories in-calories out” narrative. Eating earlier in the evening (finishing either before 5pm or before 7pm) was associated with significant improvements in body weight, BMI, body fat percentage, waist circumference, blood pressure and metabolic markers (molecules in your blood like glucose, insulin and triglycerides, which can give a picture of how your metabolism is working).

Could this be due to eating fewer calories by those who ate earlier in the evening? Not exactly – several of the trials showed that even without eating less overall, eating within a certain window of time during the day resulted in better markers of metabolic health such as levels of fasting blood glucose, fasting insulin and triglycerides. Basically, an eating pattern earlier before bedtime has independent positive effects.

The researchers offer their explanation. First, the body manages sugar better earlier in the day, so the same meal causes a higher blood sugar spike at night compared with the morning. Studies have shown that the body releases the most insulin – the hormone that helps move sugar from blood into cells – from 12-6pm, and the lowest during sleep. Quite simply, because of how our hormones are secreted, we have a better handle over food intake in the morning and afternoon, compared with the evening and night.

Depending on how you read the findings, it might make your life easier or harder. Harder practically and socially: who can actually eat dinner before 5pm, or even 7pm, given how modern life is structured and wanting to eat together with family or friends? Late shift work makes this pretty much impossible, as can work and social commitments. If you really want that piece of cake, or croissant, it’s better to have it earlier in the day. I’m not saying have chocolate for breakfast, but I am saying that if you’re going to eat chocolate tomorrow, maybe have it before 5pm when your body’s better primed to deal with it.

  • Prof Devi Sridhar is chair of global public health at the University of Edinburgh, and the author of How Not to Die (Too Soon)