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The Guardian

Rory McIlroy surges into six-shot Masters lead with stunning second-round flourish ‘That’ll be the end’: actor Sam Neill joins fight to stop controversial goldmine near his New Zealand vineyard Roberto De Zerbi targets ‘Ange-ball’ revival to save Spurs from relegation Bath hit back to reach semi-final after stunning Northampton in 11-try epic Secret Garden to Outcome: the week in rave reviews Zebras, wealth and power: Hungary’s election tests Orbán’s grip on power ‘TikTok effect’ brings sellout crowds and younger fans to Grand National meeting The war over Omagh’s gold: the £21bn mine plan tearing a community apart Britain’s shadow workforce is paid as little as 65p an hour. Who cares for the carers? From You, Me & Tuscany to Euphoria: your complete entertainment guide to the week ahead Six great reads: the man who let snakes bite him, masked heavy metal and the brutal reality for foreign students in the UK American Classic review – I defy you not to fall in love with Kevin Kline and Laura Linney’s tender comedy Cuba’s doctors were a lifeline for the world. Now the Caribbean is shamefully complicit in the US drive to expel them An environmental disaster in Moldova has Russia’s fingerprints all over it RMIT drops misconduct case against student who accused university of being ‘complicit in Gaza genocide’ Ichiro Suzuki statue unveiling goes awry as bronze bat snaps during ceremony Survivors of Epstein’s abuse accuse Melania Trump of ‘shifting burden’ on to victims European football: Real Madrid held at home by Girona to extend winless run Arne Slot insists he is ‘aligned’ with Liverpool board and fans as squad is rebuilt Kamala Harris ‘thinking about’ running for president again in 2028 JD Vance warns Iran against trying to ‘play’ the US in peace talks West Ham double up twice to thrash Wolves and put Spurs in relegation zone Trump administration releases new renderings of so-called ‘Arc de Trump’ Crispin Odey drops £79m libel claim against FT over sexual misconduct allegations Bafta apologises for events surrounding John Davidson’s Tourette’s outburst Cocktail of the week: Bar Shrimp’s la rosita – recipe New drug may extend survival in aggressive ovarian cancer, trial shows One dead and 27 injured after bus with British passengers crashes in Canary Islands Pope adds to Smith’s mass of Surrey runs with England woes a world away OpenAI CEO Sam Altman’s home targeted with molotov cocktail
Is it true that … only overweight people are at risk of h...
Kate Lloyd · 2026-04-20 · via The Guardian

Cholesterol, a fatty substance mostly made by the liver and used by the body to build cells and produce hormones, has become a heart-health bogeyman. There are several types, but high levels of LDL (low-density lipoprotein) cholesterol increase the risk of heart attack and stroke. Often labelled “bad” cholesterol, LDL builds up over time on artery walls, narrowing them and restricting blood flow.

High LDL cholesterol is not confined to people who are overweight. “Genetics are the main driver of higher LDL cholesterol levels,” says Naveed Sattar, professor of cardiometabolic medicine at the University of Glasgow. “Diets have smaller effects and it’s not necessarily the total calories that count; it’s the amount of saturated fat.” (Found in cakes, biscuits, chocolate and many ultra-processed foods, saturated fat can raise LDL levels.) All of this means someone relatively lean can still have high cholesterol, either because of their genetic profile or dietary pattern.

“Obesity per se has minimal effect on LDL cholesterol levels,” says Sattar. “But it affects other blood lipids [types of fatty substances, including cholesterol] much more.” In particular, excess body fat is linked to higher levels of triglycerides and remnant cholesterol, both of which increase the risk of cardiovascular disease. Obesity is also closely tied to conditions such as type 2 diabetes and high blood pressure, which can also make LDL more harmful.

Worried about cholesterol? From the age of 40, people in the UK are eligible for an NHS health check, which includes a cholesterol test. “Your GP can easily assess your overall cardiovascular risk,” says Sattar. “Because it’s not just about LDL – factors such as diabetes, weight and blood pressure all play a part.” Before then, it’s worth finding out if you have a family history of early heart disease.