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The Guardian

Rory McIlroy surges into six-shot Masters lead with stunning second-round flourish ‘That’ll be the end’: actor Sam Neill joins fight to stop controversial goldmine near his New Zealand vineyard Roberto De Zerbi targets ‘Ange-ball’ revival to save Spurs from relegation Bath hit back to reach semi-final after stunning Northampton in 11-try epic Secret Garden to Outcome: the week in rave reviews Zebras, wealth and power: Hungary’s election tests Orbán’s grip on power ‘TikTok effect’ brings sellout crowds and younger fans to Grand National meeting The war over Omagh’s gold: the £21bn mine plan tearing a community apart Britain’s shadow workforce is paid as little as 65p an hour. Who cares for the carers? From You, Me & Tuscany to Euphoria: your complete entertainment guide to the week ahead Six great reads: the man who let snakes bite him, masked heavy metal and the brutal reality for foreign students in the UK American Classic review – I defy you not to fall in love with Kevin Kline and Laura Linney’s tender comedy Cuba’s doctors were a lifeline for the world. Now the Caribbean is shamefully complicit in the US drive to expel them An environmental disaster in Moldova has Russia’s fingerprints all over it RMIT drops misconduct case against student who accused university of being ‘complicit in Gaza genocide’ Ichiro Suzuki statue unveiling goes awry as bronze bat snaps during ceremony Survivors of Epstein’s abuse accuse Melania Trump of ‘shifting burden’ on to victims European football: Real Madrid held at home by Girona to extend winless run Arne Slot insists he is ‘aligned’ with Liverpool board and fans as squad is rebuilt Kamala Harris ‘thinking about’ running for president again in 2028 JD Vance warns Iran against trying to ‘play’ the US in peace talks West Ham double up twice to thrash Wolves and put Spurs in relegation zone Trump administration releases new renderings of so-called ‘Arc de Trump’ Crispin Odey drops £79m libel claim against FT over sexual misconduct allegations Bafta apologises for events surrounding John Davidson’s Tourette’s outburst Cocktail of the week: Bar Shrimp’s la rosita – recipe New drug may extend survival in aggressive ovarian cancer, trial shows One dead and 27 injured after bus with British passengers crashes in Canary Islands Pope adds to Smith’s mass of Surrey runs with England woes a world away OpenAI CEO Sam Altman’s home targeted with molotov cocktail Reform UK local election candidate was twice disciplined by Tories over ‘racist comments’ Remaining in Nato is in best interests of US, says Keir Starmer Prince Harry sued for defamation by charity he co-founded Anthropic’s new AI tool has implications for us all – whether we can use it or not Concerns raised about motorbike tourist trail after death of British teenager in Vietnam The Guardian view on Trump’s civilisational threats: the words that fuel war must be condemned The Guardian view on dystopias for our times: the American nightmare Doctors’ leader claims new reduced pay offer killed chances of ending strikes in England Netanyahu-ism has achieved nothing for Israelis – and come at a monstrously high price Deborah Levy: ‘CS Lewis’s White Witch terrified me – but I wanted to meet her’ How I Shop with Michelle Ogundehin: ‘We grownups have enough stuff already’ Trump’s war and Melania’s Epstein statement, with US editor Betsy Reed – The Latest We have to stop killer motorists on Britain’s roads UK starts crackdown on EU citizens’ post-Brexit rights Londoners aren’t unfriendly – but don’t compare us to New Yorkers The religious right and the perversion of faith Artemis II images reignite moon mission memories Orbán and Magyar trade accusations in last days of Hungary election campaign Reckonwrong: How Long Has It Been? review | Safi Bugel's experimental album of the month Martin Rowson on Middle East peace talks – cartoon Masters magic, the Grand National and Premier League drama – follow with us Fears of UK and EU flight cancellations as airports warn of jet fuel shortages Reform’s petulance over slavery reparations shows it just doesn’t grasp Britain’s place in the modern world Peers vote to ban pornography depicting sex acts between stepfamily members Starbucks’s retail arm gets £13.7m tax credit even as sales increase Flyby review – interstellar musical is a voyage of epic strangeness Grand National preview: Jagwar can deny Irish cohort in Aintree classic Week in wildlife: an ostrich on the lam, a tortoise crossing a road and surfing seals Anger as swifts’ nesting holes in Derbyshire rail viaduct ‘blocked up’ Peter Mandelson faces fixed-penalty notice for urinating in public ‘There’s no shortage of terrifying technology’: how AI became TV drama’s new go-to villain ‘Fresher than anything in a shop’: the best recipe boxes and meal kits for time-poor foodies, tested Who was Hilma? 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But there’s more to it than meets the eye Reich: The Sextets album review – Colin Currie celebrates the minimalist master’s joy of six Benjamina Ebuehi’s sweet and salty chocolate chip cookies recipe Experience: my house was taken over by 70,000 bees Malcolm in the Middle: Life’s Still Unfair review – the TV magic they’ve created here is absolutely miraculous Lava bursts forth as Hawaii’s Kilauea volcano erupts Sonos review: Are these the best portable speakers that money can buy? I tested to find out Buy bread in the evening, hit the sales on a Tuesday: retail workers’ top tips to cut your shopping bill The best water flossers in the UK, tested for that dentist-clean feeling Where to start with: Muriel Spark You be the judge: should my girlfriend stop mixing gold and silver jewellery? 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A dead person’s fat pumped into your body? Why the ‘zombie filler’ trend has some experts spooked | Antiviral
Melissa Dave · 2026-04-28 · via The Guardian

With people getting everything from salmon sperm to plasma injected into their faces in the name of beauty, it is difficult to be surprised when new, even seemingly extreme methods to achieve youthfulness are promoted.

But Dr David Sparks, a specialist plastic surgeon based in Queensland, was alarmed when he heard patients were asking about cadaver fillers, a trend being promoted on social media as “zombie filler”.

“This is being presented as an established procedure, when the human clinical data is still very early,” he said.

What is zombie filler?

Fat injections, or lipofilling, is a known cosmetic procedure that involves taking fat from the patient’s own body and injecting it into the same patient’s face to add plumpness and reduce wrinkles.

But in order to be less invasive and reduce recovery time and scarring from fat removal, some cosmetic and plastic surgeons in the US are using donor adipose (fat) tissue from dead bodies.

Despite some Australians asking about the procedure in online forums and at appointments with specialist doctors, Sparks says the service isn’t approved in Australia. “The clinical evidence is still early stage, and it simply isn’t something that can be legitimately offered here yet,” he says.

“Neither AlloClae nor Renuva, the two products available in the United States, are listed on the Australian Register of Therapeutic Goods. There’s no Therapeutic Goods Administration-registered injectable adipose allograft product in Australia.”

How does the body respond to donor fat?

The procedure has only been available via a select group of cosmetic surgeons in the US as of last year, which means there is no long term data from large numbers of people about how the body responds to the filler over time.

Dr Deshan Sebaratnam, a dermatologist and associate professor at the University of New South Wales, says ideally there would be randomised controlled trials into a new treatment, where neither the researcher nor patient will know whether they are being given the new treatment, to avoid the placebo effect. This data is then peer-reviewed and made available through publishing in a scientific journal.

“I’d like to see more long-term data in terms of safety and effectiveness,” Sebaratnam said.

Sparks says there is a “gap between what’s being claimed online and what the evidence actually supports” about the procedure.

What are the safety risks?

Normally, Sebaratnam says, you can’t just transfer one person’s body part to another person because the body will recognise it as foreign, prompting an attack by the immune system and rejection.

Sparks says cadaver filler undergoes a process to prevent this risk.

While the “cadaver” framing is “technically accurate”, Sparks says it sensationalises “what is actually a carefully processed medical product … for AlloClae specifically, donor fat is treated with a detergent solution that strips the cells of their DNA”.

The structure of the cells is preserved, leaving a kind of “scaffold” made up of proteins.

Once this filler is injected, the patient’s own body gradually fills the scaffold with its own fat cells over time, he says.

Dr Lily Vrtik, president of the Australasian Society of Aesthetic Plastic Surgeons, says the procedure is still not risk-free even after this cleansing process.

“The usual risks associated with using cadaveric tissue allografts include specific issues such as tissue rejection and transmission of communicable diseases,” she says.

“More general issues include infection, failure to ‘take’ or integrate into native tissue, survival of the graft and other complications associated with surgery in general.”

Sparks says the more established and therefore safer option is still to use a patient’s own fat.

A question of ethics

Sparks says it is worth noting that donor-derived tissue isn’t new, and is already used routinely in surgery. For example, rib cartilage allograft in rhinoplasty, and tendon allograft in knee reconstruction.

“What’s novel here is the tissue type and the processing method,” he says.

However, even if the procedure eventually proves safe and effective, Sebaratnam says he has ethical reservations.

“Do the people donating their bodies know what it’s going to be used for?” he says.

“It’s one thing to sign up to be a kidney donor. It’s another for grandma’s body to be used to help boost someone’s hot photos on Instagram.”

Ivanka Prichard, a professor of body image and health with Flinders University, said she fears content promoting such cosmetic procedures can make them seem normal.

“If someone doesn’t measure up to the content that they are viewing when they compare themselves to it, this can make people feel dissatisfied with their bodies and as a result want to use cosmetic enhancements regardless of the risks,” she said.

“These impacts on body image could in turn lead to disordered eating, body dysmorphia, depression and appearance anxiety.”

  • Melissa Davey is Guardian Australia’s medical editor

  • Antiviral is a fortnightly column that interrogates the evidence behind the health headlines and factchecks popular wellness claims