WASHINGTON, D.C. – July 22, 2026 – HPE (NYSE: HPE) today announced it has been selected to participate in multiple key research and development (R&D) projects in the first phase of the U.S. Department of Energy’s Genesis Mission. The awarded projects focus on advancing AI innovation and scientific discovery across AI model application, performance optimization, networking, cybersecurity, and water availability.
In addition to contributing to critical R&D, HPE is delivering some of the world’s most powerful machines to accelerate national AI efforts as part of Genesis Mission. These fully integrated systems include the upcoming “Lux,” which is expected to be the first dedicated AI system for science supporting Genesis Mission. HPE will deliver Lux in collaboration with AMD and Oak Ridge National Laboratory.
The Genesis Mission is a historic national initiative led by the U.S. Department of Energy, which is building the world’s most powerful integrated science discovery platform. By uniting government, industry, academia, and philanthropy, it is accelerating breakthroughs in energy, scientific discovery, and national security through a new platform that combines AI, supercomputing, quantum systems, and advanced scientific instruments.
The primary goal is to identify promising pathways toward transformative scientific capabilities and to establish a foundation for future investment and scalability. HPE will collaborate with project teams to design and demonstrate research workflows that integrate AI with scientific investigation, rigorously evaluating whether these approaches can accelerate discovery, enhance predictive capabilities, improve experimentation, or generate new scientific insights.
To date, HPE has been invited to participate in the following projects:
“We have a deep, decades-long R&D partnership with the U.S. Department of Energy and its national laboratories that has ushered in world-leading innovation in scientific computing,” said Andrew Wheeler, deputy CTO, senior vice president and director of HPE Labs. “We’re proud to expand our R&D collaboration, on top of delivering cutting-edge integrated AI systems, to contribute to the Genesis Mission and accelerate the nation’s AI-driven science and engineering initiatives.”
HPE’s involvement underscores its commitment to pioneering innovative technologies that support sovereign AI and the future of scientific research and discovery.
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