Imagine losing a finger in a kitchen mishap or an entire limb in an accident. Instead of learning to adapt to a prosthetic, your doctor prescribes you a serum. A few months later, your bone, muscle, nerves, and skin have perfectly knit themselves back together. Your limb is entirely regrown.
It sounds like pure science fiction, but scientists are currently working to unlock the secrets of limb regeneration in mammals, drawing inspiration from salamanders. Axolotls, a type of salamander, can take roughly 40 to 50 days to regrow lost limbs, which is a flash compared to humans and other mammals who lack the ability all together. But a new treatment could change that shortcoming.
In a recent study published in Nature Communications, researchers from Texas A&M University used a specially-formulated serum that encouraged mice to form a blastema—the temporary cellular structure that helps organisms like axolotls regenerate structures.
How were they able to do this? According to study author Ken Muneoka, PhD, professor of veterinary physiology and pharmacology at Texas A&M, he and his team amputated part of a mouse’s finger. From there, researchers followed three steps to regrow the digit:
So, could someone who is born with, say, an underdeveloped limb be able to grow a new one using this treatment—or does the human body lack the blueprint? According to Muneoka, it depends on the reason for the underdeveloped limb.
“The human body uses the ‘blueprint’ to form the limb in the embryo, and we found evidence that this ‘blueprint’ is re-utilized when regeneration is stimulated by our treatment,” Muneoka says. In other words, someone whose limb was underdeveloped because of external factors in vivo, such as alcohol or drug exposure, might see better results than someone whose underdeveloped limb was caused by a genetic modification—or a damaged blueprint. “If the ‘blueprint’ is intact, then the expectation is that the regeneration should be possible,” he says. The amount of time this would take isn’t yet known.
If this treatment has the potential to regrow human limbs, what else could it do? Could it eventually be used to regrow more complex structures, like organs? There are studies—such as one published in Nature Genetics and another in PNAS—that show lung formation and limb formation share similar genetic requirements, according to Muneoka. There’s also research in salamanders that show that two proteins that are important for limb regeneration are also important for regeneration of other structures, such as gills.
“This suggests that the regenerative process may have universal characteristics, which gives us hope that our strategy for stimulating digit regeneration could have broad application,” Muneoka says. “We believe that our study outlines a general strategy for enhancing regenerative capabilities in humans. The specific details for this strategy will likely differ between organ systems, and that needs to be determined empirically.”
The tricky part, Muneoka says, is that organ regeneration requires time that may not be possible if the organ’s use is required to stay alive. So depending on the extent of the organ’s damage, a transplant from a donor may still be necessary.
Regeneration of body parts is unlikely to lead to immortality, though, according to Muneoka. “If individuals could regenerate organs throughout their lives, it would improve the quality of life, and it may enhance lifespan,” he says. But he points to a 2021 mouse study that he worked on, which found that blastema formation and the quality of the regenerative response declines with age.
So while we won’t be able to live forever or sprout a new pair of lungs overnight, the blueprint for human regeneration is already coded inside us—an exciting step forward for what’s possible when it comes to human healing.
February / March 2026
This issue is optimized for mobile/tablet viewing. It's also available on Apple News+.
Featuring:
➡ Archaeologists Found a Skeleton Wearing a Silver Amulet. The Discovery Is Rewriting the History of Christianity.
➡ The Stray Dogs of Chernobyl Are Rapidly Mutating. Scientists Are Still Trying to Figure Out What It Means.
➡ New Evidence Could Upend What We Know About the Charles Lindbergh Baby Murder
➡ Police Found Mysterious Notes in a Dead Man's Pocket. They Turned Out to Be Codes That Not Even the FBI Can Break.
December 2025 / January 2026
This issue is optimized for mobile/tablet viewing. It's also available on Apple News+.
Featuring:
➡ An Angel of Death Preyed on Hospital Patients for Years.
➡ How America's Most Advanced Lab Brought the Killer to Justice.
➡ A 3,000-Ton Locomotive Was Loose, Unstoppable, and Filled With Toxic Cargo
➡ An Underwater Cave Promised Adventure and Glory. No One Expected It to Become a Tomb.
➡ Your Consciousness Can Predict the Future, Some Scientists Say
October / November 2025
This issue is optimized for mobile/tablet viewing. It's also available on Apple News+.
Featuring:
➡ Inside the Secret Island Where Death Is Optional
➡ A Legendary Ship Sank Without Warning. Fifty Years Later, Science Could Finally Solve the Mystery of the Edmund Fitzgerald.
➡ This Tech Rebel Threw Away $900 Million in a Municipal Dump. Can Robots Find His Lost Fortune?
➡ Sex Workers, LSD, and Mind Control: What Happened in the CIA's Lab of Nightmares at 225 Chestnut Street
August / September 2025
This issue is optimized for mobile/tablet viewing. It's also available on Apple News+.
Featuring:
➡ The Worst Air Disaster in American History Happened in Broad Daylight. Will More Mistakes Keep Happening?
➡ NASA Has a Plan to Save Earth from Planet-Destroying Asteroids. It Sounds Even Wilder than Science Fiction.
➡ A Naval Officer Says Underwater UFOs Are Legitimate Threats. The Evidence Is Hard to Ignore.
➡ When You Die, a Psychedelic Molecule Shapes Your Final Moments of Consciousness, a New Theory Reveals.
June/July 2025
This issue is optimized for mobile/tablet viewing. It's also available on Apple News+.
Featuring:
➡ This Undersea Explorer Found America's Greatest Sunken Treasure. Then Things Got Really Weird.
➡ Is Bigfoot Hiding in the Swamps of Florida? This Group Says It Has Proof.
➡ Scientists May Have Gotten the Global-Warming Timeline Seriously Wrong.
➡ A Third State Now Exists Between Life and Death, Some Scientists Now Believe
April/May 2025
This issue is optimized for mobile/tablet viewing. It's also available on Apple News+.
Featuring:
➡ Scientists Successfully Revive a Dead Brain, Redefining the Boundary Between Life and Death
➡ Fingerprints Keep Leading to Wrongful Convictions. Why Do Courts Still Rely on Them?
➡ For 80 Years, the North Sea Held a Deadly Killer. Now Scientists Are Racing to Defuse the Threat.
➡ They Built the Quietest Room in the World. Why Is Everyone So Afraid to Step Inside It?
February/March 2025
This issue is optimized for mobile/tablet viewing. It's also available on Apple News+.
Featuring:
➡ This Guy Says He Knows the Truth About UFOs. Should We Believe Him?
➡ Scientists Are Now One Step Away From Solving Nuclear Fusion—And Unlocking Unlimited Energy.
➡ A Million-Dollar Heist Rocked the Art World— Then Amateur Sleuths Cracked the Case
➡ A New Era of Missile Warfare Has Begun—and the U.S. Isn’t Ready
December/January 2025
This issue is optimized for mobile/tablet viewing.
It's also available on Apple News+.
Featuring:
➡ A Clue Hidden in a 400-Year-Old Map Might Have Just Solved One of America's Greatest Mysteries
➡ Inside the Deranged Plot to Smuggle Cocaine With an Armed Soviet-Era Submarine
➡ This Brilliant Engineer Helped Build the B2 Bomber—Then He Sold America's Stealth Secrets to China
➡ Your Consciousness Can Connect With the Whole Universe
October/November 2024
This issue is optimized for mobile/tablet viewing.
It's also available on Apple News+.
Featuring:
➡Untold Secrets Reveal How the Castle Bravo Test Became America’s Worst Nuclear Disaster
➡ This Body Was Found Preserved on a Block of Ice in a Colorado Shed. It Had Been There for 30 Years.
➡ It Was Supposed to Be America's Greatest Victory in Space—Then It Became NASA’s Worst Nightmare
➡ The Sidewinder Missile Ruled the Air—Then the Soviets Stole the Design
August/September 2024
This issue is optimized for mobile/tablet viewing. It's also available on Apple News+.
Featuring:
➡This Man Knows the Truth About Amelia Earhart. Why Doesn't Anyone Believe Him?
➡ The Army's Machine Gun Is No Match for Cheap Chinese Body Armor. So It's Making a New One.
➡ Russia Built a Stunning Rival to the Supersonic Concorde—and Then It Fell From the Sky
➡ A Navy Admiral Says Underwater UFOs Are a Threat—and the Pentagon is Withholding Secrets
June / July 2024
This issue is optimized for mobile/tablet viewing. It's also available on Apple News+.
Featuring:
➡4 Black Eggs Have Surfaced From the Depths of the Ocean— and the Mysterious Creatures Inside Are Baffling Science
➡ A $2 Million Treasure Appeared in a Kentucky Cornfield. No One Knows Where It Came From.
➡ A Million-Dollar Heist Rocked the Art World— Then Amateur Sleuths Cracked the Case
➡ A New Era of Missile Warfare Has Begun—and the U.S. Isn’t Ready
April May / 2024
This issue is optimized for mobile/tablet viewing. It's also available on Apple News+.
Featuring:
➡The Man Who Knows Too Much About Area 51
➡ How the FBI Took Down the Internet's Most Dangerous Website
➡ A Staggering New Clue Emerges in the D.B. Cooper Hijacking Mystery
➡ The Wildest Prison Break in U.S. History
➡ The Secret to a Perfect Lawn Lies in One of These 10 Electric Lawnmowers
February / March 2024
This issue is optimized for mobile/tablet viewing. It's also available on Apple News+.
Featuring:
➡The Incredible Mystery of NASA’s Missing Moondust
➡ Inside the Final Fiery Minutes of the East Palestine Train Wreck
➡ Scientists Believe They’ve Unlocked Consciousness—and It Connects to the Entire Universe
➡ Why This Unstoppable Stealth Bomber Will Rule the Skies
➡ America Is Developing a New Nuclear Bomb—But Can’t Test Whether It Works
➡ The 8 Best, Expert-Recommended Solar-Powered Generators
Special Issue: Nukes
➡ How Deadly Nuclear Waste Is Menacing This St. Louis Neighborhood
➡ The Terrifying History of Russia's Nuclear Submarine Graveyard
➡ Strange Mutations in Stray Dogs Near Chernobyl Suggest They Are Rapidly Evolving
➡ America Dumped 56 Million Gallons of Radioactive Material Along the Columbia River—Then It Started to Leak
December 2023 / January 2024
This issue is optimized for mobile/tablet viewing. It's also available on Apple News+.
Featuring:
➡ A New Clue In Amelia Earhart's Disappearance Emerges From the Ocean
➡ How an Alleged Water Bandit Stole $25 Million in Water from Thirsty California Farms
➡ A Coal Mine Exploded and 300 Miners Died. What Went Wrong?
➡ China Just Built a Terrifying New Aircraft Carrier and May Soon Dominate the Seas
October / November 2023
This issue is optimized for mobile/tablet viewing. It's also available on Apple News+.
Featuring:
➡ How Rats Took Over Our Cities—And Why We Can't Stop Them
➡ This Language Is on the Verge of Extinction. Can It Be Saved?
➡ America's Deadliest Warplane Returns in a New Doomsday Role
➡ This Amateur Diving Group Kept Solving Cold Cases. Then Its Own Skeletons Surfaced.
➡ The Scientific Breakthrough That Could Put an End to Gray Hair.
August/September 2023
This issue is optimized for mobile/tablet viewing. It's also available on Apple News+.
Featuring:
➡ Immortality Is in Reach. But It’s Not What We Imagined.
➡ Your Next iPhone (and Nuclear Subs) Will Be Powered By Space Metal
➡Scientists Now Think We Can Build a Warp Drive
➡ China and Russia Have Cracked the Stealth Code. Can the U.S. Regain Air Dominance?
June/July 2023
This issue is optimized for mobile/tablet viewing. It's also available on Apple News+.
Featuring:
➡ The CIA’s Secret Plan to Build a Laser Beam Powered by the Human Mind
➡ The 747 Ruled the Skies—Then One Slammed Into a Mountain
➡The Race to Contain AI Before Singularity
➡ These Florida Homes Aren’t Just Hurricane-Proof—They’re Blueprints for the Future
April/May 2023
This issue is optimized for mobile/tablet viewing. It's also available on Apple News+.
Featuring:
➡ AI Is on the Cusp of Taking Control—This Is How It May All Go Wrong
➡ There’s No Weapon Russia Fears More Than the HIMARS Rocket Launcher
➡The Nuclear-Submarine Arms Race Is Getting Intense, and the U.S. Just Took a Massive Leap Forward
➡ Iran Is Becoming a Drone Superpower—By Stealing American Technology
February/March 2023
This issue is optimized for mobile/tablet viewing. It's also available on Apple News+.
Featuring:
➡ The Greatest Treasure Hunt in American History Ended—and Then Things Got Weird
➡ These Are the High-Powered Weapons Ukraine Needs to Send Russia Running
➡ The Secret War to Take Out Iran’s Fleet of F-14 Jets
➡ Russia Is Trying to Intimidate the U.S. with Hypersonic Missiles and Big, Scary Nukes—And It's More Than a Threat
December 2022/January 2023
This issue is optimized for mobile/tablet viewing. It's also available on Apple News+.
Featuring:
➡ Is Death Real?
➡ China and Russia Are Dominating the Hypersonic Arms Race—And It’s Not Even Close
➡ When the South Fork Dam Broke, a Pennsylvania City Washed Away. Which Town Is Next?
➡ The Navy’s New $13 Billion Aircraft Carrier Is Already Obsolete. This Weapon Can Save It.
October/November 2022
This issue is optimized for mobile/tablet viewing. It's also available on Apple News+.
Featuring:
➡ Can America's M1 Abrams Still Compete With China's and Russia's Latest Battle Tanks?
➡ Inside the Final Minutes of the Concorde Disaster—and How It Doomed Supersonic Travel for Decades
➡ How the Massive Cargo Ship Felicity Ace Sank, Taking $400 Million Worth of Exotic Supercars With It
➡ I Turned My Old Gas-Guzzler Into a Zippy EV for $15,000
August/September 2022
This issue is optimized for mobile/tablet viewing. It's also available on Apple News+.
Featuring:
➡ Cosmic Secrets of the 17 Most Powerful Mega-Telescopes on Earth—and Beyond
➡ Can the Air Force's Secret, Hypersonic Jet Reclaim the Skies From Russia and China?
➡ For 50 Years, the Zodiac Killer's 340 Cipher Stumped the FBI—Then Three Amateurs Cracked the Code
➡ America's Most Fearsome Howitzer Has Entered the War in Ukraine
June/July 2022
This issue is optimized for mobile/tablet viewing. It's also available on Apple News+.
Featuring:
➡ Every Single Drone Fighting in the Skies Over Ukraine
➡ How to Buy a New Car in 2022 Without Getting Fleeced
➡ This Megastructure Could Keep Us Alive Forever
➡ The Race to Revolutionize EV Batteries
Danielle Zickl is a freelance writer who has 10 years of experience covering fitness, health, and nutrition. She's a graduate of Ithaca College. You can find her work here on Women's Health, and in many other publications including PS, SELF, Well+Good, Runner’s World, Outside RUN, Peloton, Men’s Fitness, and more.
此内容由惯性聚合(RSS阅读器)自动聚合整理，仅供阅读参考。 原文来自 — 版权归原作者所有。