I’ve been gaining weight again. More than twenty pounds in the last ~4 months.

I’ve been hitting the gym hard and getting measurably stronger, so: Food! See, your boy can eat. The amount I can eat before I feel full would astound most of you out there. Whatever you think of as a complete hearty meal, sure as you’re born, ain’t gonna get me there.

Being fat comes with one (1) society-regimented bucket of shame. People look away. It’s a thing.

I had gone off my last round of GLP-1 drugs because I was doing OK, and it had lost its effectiveness. I’m not sure if it’s everyone’s experience, but it’s mine, and it’s happened a couple of times now. Honestly, I think my I CAN EAT THROUGH OZEMPIC line of XXXL T-Shirts has a chance. These drugs work very well for a bit. I like them because it gives me a glimpse of what it’s like to be a regular person who eats a regular amount of food and feels a regular amount of full. You settle into that for a while with these drugs.

But, in time, effectiveness wanes. And the pharmacies have an answer: higher doses! All these GLP-1 drugs, and I’m pretty sure it is all of them, have dosage tiers. The three I’ve tried have three tiers.

Ozempic rolls like this:

Wegovy is getting in on the action:

Mounjaro has even more layers:

Again, they do this because it loses effectiveness. I don’t think people quite realize this??? Even though it’s not hidden in any way.

I think these drugs are pretty amazing, and I’m proud of science for starting to figure all this out, but I’m also a little sick of hearing about how airlines are going to spend less money on fuel now. I’ve been reading this story for many years. It’s laughable when we literally know they don’t work permanently.

Look at those graphics above. This isn’t a forever solution yet. They are literally showing and telling us that. There is no answer once they lose effectiveness. Perhaps controversial, but I think overeating, in the form I experience it, is an addiction, and addictions come back. Is it possible to beat it? Absolutely. Is it likely? No.

I hope you don’t know firsthand, but I bet you already know that cocaine doesn’t maintain effectiveness, either. You need a second line for the same thrill before long. It doesn’t end well.

Anyway, I’m back on GLP-1s.

At least they work for a while, and that while feels pretty good.

It was a rough start, though. My doctor agreed it’s good for me and we should kick up the dosage based on the waned effectiveness. Wegovy this time. It was this past Tuesday that I picked up the meds. It’s down to $350 now! It used to be like $1,200 without insurance. I jabbed myself Tuesday night at about 8pm.

I was hugging the toilet hard by midnight. That was a first.

See, there was a lot of food in my body. I remember lunch that day, where I made a sandwich were my rational brain saw it and thought that’s 2-3 sandwiches. But of course I ate all of it. And one of those salad bags that make a Caesar salad for a family of four. And a pint of cottage cheese. And a bag of Doritos. I was full after that, but the trick is just to switch to sugar after that, and I can keep going. It wasn’t quite noon, and I had a decent breakfast in me already. I ate dinner that night as well.

So when the Wegovy started to hit, which tells your body you’re full when you eat a celery stick, it told my body that it was about to pop. I puked in four sessions over 24 hours.

Now it’s Friday, and I’ve barely eaten since. I’ve eaten a little. Like, I’m fine. It’s just weird.

I’m miscalibrated.

On my own, nature, nurture, whatever you think, my current body is miscalibrated. It doesn’t do food correctly.

On GLP-1 drugs, I’m also miscalibrated. My body doesn’t do food correctly. It highly overcorrects. That can feel good for a while. I don’t wanna be skinny, I just wanna be normal. I want to eat, and stop eating, like a calibrated person.