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EU agrees to simpler AI rules and complete ‘nudification’ ban Tissue repair therapy Substrato wins best pitch at EI Start-Up Day Major European markets still lagging on salary transparency, finds report Anthropic joins forces with SpaceX for Colossus capacity Enterprise Ireland pumped €33m into home-grown start-ups in 2025 Coimisiún na Meán opens investigation into Meta’s content promotion German quantum computing start-up Eleqtron raises €57m Dublin’s GridBeyond to support energy efficiency with new global headquarters What’s the difference between IT and OT security? 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7 Irish start-ups transforming the manufacturing floor
Suhasini Srinivasaragavan · 2026-06-12 · via Technology – Silicon Republic

From connected factory floors to automation and digital twins, ‘Industry 4.0’ refers to the future of manufacturing.

Click here to see the full collection of Industry 4.0 Focus stories.

Ireland’s diverse manufacturing industry makes it the choice European location for a growing number of industrial and technology companies, according to IDA Ireland.

It does especially well in some sectors – medtech, automotives, aerospace and chemicals being a few examples – with its capacity only enhanced by a steady supply of skilled talent emerging from third-level institutions.

Meanwhile, a strong talent pipeline supported by grants and commercialisation support for research and innovation also allows Ireland to maintain its appeal as a global manufacturer.

From connected factory floors and industrial IoT to AI-powered automation and digital twins, ‘Industry 4.0’ is a phrase used to refer to the future of manufacturing. Here are seven Irish start-ups innovating on the factory floor.

Forge Robotics

This Galway start-up is a part of the prestigious Y Combinator accelerator programme behind the likes of Airbnb, Stripe and Uber.

Founded by CEO Eoin Cobbe and CTO Robert Cormican, Forge Robotics wants to tackle the rising threat of skilled welder shortages in manufacturing using intelligent automation.

The company makes an AI-powered intelligence layer that improves the welding capabilities of industrial robots. Its system allows robots to scan a part, interpret its geometry and execute welds even when the set-up is imperfect.

Gemell Technology

Headquartered in Dublin’s Dogpatch Labs, this Enterprise Ireland (EI) ‘High Potential Start-Up’ builds 3D visualisation and sustainability software for textile manufacturers and designers.

Gemell Technology aims for its technology to significantly reduce unnecessary fabric samples from ending up in landfills.

The company can generate photo-like digital models of yarns and fabrics, which manufacturers can tweak instead of ordering physical fabric samples. These 3D renders are generated with fabric textures originating from individual fibres.

Gemell claims that manufacturers that use its technology reduce unnecessary fabric samples and waste by 70pc, while getting products to market 11 weeks faster.

The company has offices in Dublin and London, and came in as the first runner-up at last year’s All-Island Circular Venture Awards – a competition that recognises late-stage start-ups across the island showcasing circular value propositions.

InnaLabs

Last year, this Dublin-based space-tech secured its second contract to advance Earth’s planetary defence with the European Space Agency (ESA)’s Ramses mission.

The Rapid Apophis Mission for Space Safety – or Ramses – will rendezvous with asteroid 99942 Apophis, accompanying it during its extremely close but safe flyby of Earth in 2029.

InnaLabs’ gyroscope navigation system will be helping the ESA, the Italian aerospace engineering company OHB and the Spanish tech company GMV in the space mission scheduled for launch in April 2028.

The company’s technology solves complex navigation, stabilisation and guidance challenges within space, aerospace, land and marine markets.

Oscil

Oscil provides data analytics support for the pharmaceutical and dairy sector. The company’s founder Dr Patrick Cronin won the EI Big Ideas award last year after contesting in a pitching battle against other pre-spin-out ventures emerging from EI’s Commercialisation Fund.

Speaking to SiliconRepublic.com, Cronin said that the “current rise in weight loss drugs [and] GLP-1s are driving huge investment in the protein market”, and that “Oscil can unlock a lot of capacity and quality in spray driers through edge sensing and machine learning to provide real-time process control”.

The company said it is seeking early adopters in the spray drying industry to improve production capacity and product quality.

Smartfactory

This 2016-founded start-up captures, analyses and visualises performance indicators from the manufacturing, logistics and utility sectors using Industry 4.0 technology.

The company’s SaaS solutions, built on technology from hardware partners Siemens and Banner, help cut down on manufacturing downtime by identifying hidden losses in the production process.

It is based out of Nexus Innovation Centre at the University of Limerick.

Ubotica

This Dublin-based space-tech is a frequent collaborator with NASA and the ESA. Last month, it announced a partnership with Texas’s Novi Space to deliver real-time intelligence from the Earth’s orbit.

The collaboration enables Earth observation data to be processed directly on satellites instead of it needing to be transferred to Earth for analysis.

Ubotica is deploying its AI platform, which processes input data within 90 seconds, for the space mission. According to the company, in a single test observation of a Singapore port, the platform processed hundreds of vessels and detected those operating ‘dark’ in under two minutes.

The company has deployed its AI capabilities on numerous missions, including its own CogniSAT-6 satellite.

WrxFlo

Founded in 2019 by former Dell manufacturing leaders Tim Crowe, Ken Sheehan and Jennifer Kelly, WrxFlo is a SaaS platform tailored specifically for manufacturing and logistics operations.

The company claims its platform acts as a “digital co-worker” across operations and the vertical line of command by connecting data from across the factory, warehouse and supply chain, eliminating non-value-added tasks and surfacing ‘red’ indicators before they become costly problems.

“We built WrxFlo from first-hand experience of running complex manufacturing and supply chain operations,” said Crowe, the company’s CEO.

“WrxFlo enables industrial manufacturers and logistics operators turn complex, paper or Excel-based processes into streamlined, data-driven systems that reduce cost and improve efficiency.”

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