We consider the effect of caching in wireless networks where fading is the dominant channel effect. First, we propose a one-hop transmission strategy for cache-enabled wireless networks, which is based on exploiting multi-user diversity gain. Then, we derive a closed-form result for throughput scaling of the proposed scheme in large networks, which reveals the inherent trade-off between cache memory size and network throughput. Our results show that substantial throughput improvements are achievable in networks with sources equipped with large cache size. We also verify our analytical result through simulations.