Orthogonal Time Frequency Space (OTFS) is a framework for communications and active sensing that processes signals in the delay-Doppler (DD) domain. It is informed by 6G propagation environments, where Doppler spreads measured in kHz make it more and more difficult to estimate channels, and the standard model-dependent approach to wireless communication is starting to break down. We consider Zak-OTFS where inverse Zak transform converts information symbols mounted on DD domain pulses to the time domain for transmission. Zak-OTFS modulation is parameterized by a delay period $τ_{p}$ and a Doppler period $ν_{p}$, where the product $τ_{p}ν_{p}=1$. When the channel spread is less than the delay period, and the Doppler spread is less than the Doppler period, the Zak-OTFS input-output relation can be predicted from the response to a single pilot symbol. The highly reliable channel estimates concentrate around the pilot location, and we configure low-density parity-check (LDPC) codes that take advantage of this prior information about reliability. It is advantageous to allocate information symbols to more reliable bins in the DD domain. We report simulation results for a Veh-A channel model where it is not possible to resolve all the paths, showing that LDPC coding extends the range of Doppler spreads for which reliable model-free communication is possible. We show that LDPC coding reduces sensitivity to the choice of transmit filter, making bandwidth expansion less necessary. Finally, we compare BER performance of Zak-OTFS to that of a multicarrier approximation (MC-OTFS), showing LDPC coding amplifies the gains previously reported for uncoded transmission.