We consider a scenario where a base station (BS) attempts to collect fresh information from power constrained sensors over time-varying band-limited wireless channels. We characterize the data freshness through the recently proposed metric--the Age of Information. We consider a time-varying channel model with power adaptation. Unlike previous work, packet loss may happen due to imperfect channel estimation or decoding error. We propose an asymptotic optimal scheduling algorithm minimizing AoI performance and satisfying both bandwidth and power constraint in such networks. Numerical simulations show that the proposed policy outperforms the greedy one, and we observe that sensors with poor channels are scheduled at higher AoI in order to limit the packet loss.