We experimentally investigate mutual information and generalized mutual information for coherent optical transmission systems. The impact of the assumed channel distribution on the achievable rate is investigated for distributions in up to four dimensions. Single channel and wavelength division multiplexing (WDM) transmission over transmission links with and without inline dispersion compensation are studied. We show that for conventional WDM systems without inline dispersion compensation, a circularly symmetric complex Gaussian distribution is a good approximation of the channel. For other channels, such as with inline dispersion compensation, this is no longer true and gains in the achievable information rate are obtained by considering more sophisticated four-dimensional (4D) distributions. We also show that for nonlinear channels, gains in the achievable information rate can also be achieved by estimating the mean values of the received constellation in four dimensions. The highest gain for such channels is seen for a 4D correlated Gaussian distribution.