In this paper, we generalize the fundamental relation between the derivative of the mutual information and the minimum mean squared error (MMSE) to multiuser setups. We prove that the derivative of the mutual information with respect to the signal to noise ratio (SNR) is equal to the MMSE plus a covariance induced due to the interference, quantified by a term with respect to the cross correlation of the multiuser input estimates, the channels and the precoding matrices. We also derive new relations for the gradient of the conditional and non-conditional mutual information with respect to the MMSE. Capitalizing on the new fundamental relations, we derive closed form expressions of the mutual information for the multiuser channels, particularly the two user multiple access Gaussian channel driven by binary phase shift keying (BPSK) to illustrate and shed light on methods to derive similar expressions for higher level constellations. We capitalize on the new unveiled relation to derive the multiuser MMSE and mutual information in the low-SNR regime.