Given samples from an unknown distribution $p$, is it possible to distinguish whether $p$ belongs to some class of distributions $\mathcal{C}$ versus $p$ being far from every distribution in $\mathcal{C}$? This fundamental question has received tremendous attention in statistics, focusing primarily on asymptotic analysis, and more recently in information theory and theoretical computer science, where the emphasis has been on small sample size and computational complexity. Nevertheless, even for basic properties of distributions such as monotonicity, log-concavity, unimodality, independence, and monotone-hazard rate, the optimal sample complexity is unknown. We provide a general approach via which we obtain sample-optimal and computationally efficient testers for all these distribution families. At the core of our approach is an algorithm which solves the following problem: Given samples from an unknown distribution $p$, and a known distribution $q$, are $p$ and $q$ close in $χ^2$-distance, or far in total variation distance? The optimality of our testers is established by providing matching lower bounds with respect to both $n$ and $\varepsilon$. Finally, a necessary building block for our testers and an important byproduct of our work are the first known computationally efficient proper learners for discrete log-concave and monotone hazard rate distributions.