We consider cooperative radio access network architectures, especially distributed massive MIMO and Cloud RAN, considering their similarities and differences. We address in particular the major challenge posed to both by the implementation of a high capacity fronthaul network to link the distributed access points to the central processing unit, and consider the effect on uplink performance of quantization of received signals in order to limit fronthaul load. We use the Bussgang decomposition along with a new approach to MMSE estimation of both channel and data to provide the basis of our analysis.