As the integrated sensing and communication(ISAC) technology emerges as a promising component of sixth generation (6G), the study of its physical layer security has become a key concern for researchers. Specifically, in this work, we focus on the security issues over a multi-carrier (MC)-non-orthogonal multiple access (NOMA) assisted ISAC system, considering imperfect channel state information (CSI) of an active Eve and graded confidentiality demands for users. To this end, the subcarrier allocation, the information, and artificial noise beamforming are designed to maximize the minimum communication rate, while ensuring diverse confidentiality and sensing performance demands. An effective security strategy is devised via the Lagrangian dual transformation and successive convex approximation methods. Simulations confirm the validity and robustness of the proposed scheme in terms of the security performance.