In this paper, we study skew constacyclic codes over the ring $\mathbb{Z}_{q}R$ where $R=\mathbb{Z}_{q}+u\mathbb{Z}_{q}$, $q=p^{s}$ for a prime $p$ and $u^{2}=0$. We give the definition of these codes as subsets of the ring $\mathbb{Z}_{q}^αR^β$. Some structural properties of the skew polynomial ring $ R[x,θ]$ are discussed, where $ θ$ is an automorphism of $R$. We describe the generator polynomials of skew constacyclic codes over $ R $ and $\mathbb{Z}_{q}R$. Using Gray images of skew constacyclic codes over $\mathbb{Z}_{q}R$ we obtained some new linear codes over $\mathbb{Z}_4$. Further, we have generalized these codes to double skew constacyclic codes over $\mathbb{Z}_{q}R$.