"mdendro" is an R package that provides a comprehensive collection of linkage methods for agglomerative hierarchical clustering on a matrix of proximity data (distances or similarities), returning a multifurcated dendrogram or multidendrogram. Multidendrograms can group more than two clusters at the same time, solving the nonuniqueness problem that arises when there are ties in the data. This problem causes that different binary dendrograms are possible depending both on the order of the input data and on the criterion used to break ties. Weighted and unweighted versions of the most common linkage methods are included in the package, which also implements two parametric linkage methods. In addition, package "mdendro" provides five descriptive measures to analyze the resulting dendrograms: cophenetic correlation coefficient, space distortion ratio, agglomeration coefficient, chaining coefficient and tree balance.