The availability of metadata for scientific documents is pivotal in propelling scientific knowledge forward and for adhering to the FAIR principles (i.e. Findability, Accessibility, Interoperability, and Reusability) of research findings. However, the lack of sufficient metadata in published documents, particularly those from smaller and mid-sized publishers, hinders their accessibility. This issue is widespread in some disciplines, such as the German Social Sciences, where publications often employ diverse templates. To address this challenge, our study evaluates various feature learning and prediction methods, including natural language processing (NLP), computer vision (CV), and multimodal approaches, for extracting metadata from documents with high template variance. We aim to improve the accessibility of scientific documents and facilitate their wider use. To support our comparison of these methods, we provide comprehensive experimental results, analyzing their accuracy and efficiency in extracting metadata. Additionally, we provide valuable insights into the strengths and weaknesses of various feature learning and prediction methods, which can guide future research in this field.