Medical operations (MOs) are essential in healthcare,and they are also a big concept that includes various operations during the perioperative period.Traditional operation exposes its limitations during the perioperative period,reflected in medical training,surgical preparation,and postoperative rehabilitation.Serious Games for Medical Operation (SGMO) offer new ways and complementary solutions to support MOs.As a review,this paper analyzes the development of SGMO and considers various aspects of the SGMO,such as interface,functions,and technologies.By combining MO and serious games characteristics,the paper classifies SGMO and analyzes their features and functions for different groups of users and at various stages of the perioperative period (before,during,and after an MO).Interactive technologies used in SGMO are presented from a visual,haptic,and auditory perspective.This paper reviews the development of SGMO,summarizes its functions and technologies.Besides,it presents representative products and suggests future research directions.