This manifesto outlines key principles for progress in the post-AI era, emphasizing non-linear yet cumulative advancement, deep understanding of purpose and context, multi-stakeholder collaboration, and system-level experimentation. It redefines progress as substantial, durable, and replicable advancement, highlighting the importance of balancing technological innovation with human-centric values. It acknowledges AI's potential to accelerate progress across industries while recognizing its limitations, such as creating illusions of understanding and potentially narrowing problem-solving approaches. It concludes that true progress in the AI age requires a symbiosis of artificial intelligence capabilities and human ingenuity, calling for a holistic, interdisciplinary approach to shape a future that serves all of humanity.