A supervised learning approach is proposed for regularization of large inverse problems where the main operator is built from noisy data. This is germane to superresolution imaging via the sampling indicators of the inverse scattering theory. We aim to accelerate the spatiotemporal regularization process for this class of inverse problems to enable real-time imaging. In this approach, a neural operator maps each pattern on the right-hand side of the scattering equation to its affiliated regularization parameter. The network is trained in two steps which entails: (1) training on low-resolution regularization maps furnished by the Morozov discrepancy principle with nonoptimal thresholds, and (2) optimizing network predictions through minimization of the Tikhonov loss function regulated by the validation loss. Step 2 allows for tailoring of the approximate maps of Step 1 toward construction of higher quality images. This approach enables direct learning from test data and dispenses with the need for a-priori knowledge of the optimal regularization maps. The network, trained on low-resolution data, quickly generates dense regularization maps for high-resolution imaging. We highlight the importance of the training loss function on the network's generalizability. In particular, we demonstrate that networks informed by the logic of discrepancy principle lead to images of higher contrast. In this case, the training process involves many-objective optimization. We propose a new method to adaptively select the appropriate loss weights during training without requiring an additional optimization process. The proposed approach is synthetically examined for imaging damage evolution in an elastic plate. The results indicate that the discrepancy-informed regularization networks not only accelerate the imaging process, but also remarkably enhance the image quality in complex environments.