Non-orthogonal multiple access (NOMA) was recently proposed as a viable technology that can potentially provide the spectral efficiency, low latency, and massive connectivity requirements of future radio networks. In this context, numerous ultra-high reliability technologies such as the industrial Internet of things, smart grids, and smart homes present environments which are characterized by the presence of impulsive electromagnetic interference, known as impulsive noise. Under such conditions, the power domain multiplexing in NOMA is expected to render the system particularly sensitive to this additional impulsive noise. Therefore, in this article, we quantify the effects of impulsive noise on the outage performance of uplink NOMA systems. Extensive Monte-Carlo simulations as well as offered analytical results demonstrate the vulnerability of the involved NOMA users to this type of noise. This highlights the need for effective modeling of the impulsive noise as well as the design of mitigation techniques that are suitable for the particular demands and challenges of NOMA.