In this paper, we propose a new Multiple-Input Multiple-Output (MIMO) Molecular Communication (MC) system where multiple types of molecules are utilized for transmission and reception of information. We call the proposed framework as Multiple-type Transmission and Multiple-type Reception (MTMR). We also obtain the bit error rate (BER) of the system and an optimization problem is formulated to minimize BER by optimizing the drug dosage for designing drug release mechanism. As numerical analysis shows, the BER of MIMO-MTMR in MC is minimized to $\text{3.7}\times\text{10}^{\text{-3}}$ by considering the budget of molecules as 10000. Furthermore, MIMO-MTMR outperforms Single-type Transmission Single-type Reception MIMO from the BER performance point of view approximately 54% for time slot 10s.