According to the World Health Organization (WHO), 30 million people are in need of prosthetic and orthotic devices. Some people are born with this limb loss, while others lose limbs due to diseases such as Cancer, diabetes, and work accidents. Additionally, limb amputation is among the most severe and heavily reported injuries among veterans during war. The medical applications of integrated circuit technology have recently made significant advances, thus improving human quality of life. Moreover, the use of microelectronics integration dominates a lot of medical applications, especially portable and wearable battery-operated devices. Thus, the objective of this report is to provide the reader with the basic understanding of integrated solutions for controlling prosthetic limbs.