The mismatch between the numerical and actual nonlinear models is a challenge to nonlinear acoustic echo cancellation (NAEC) when the nonlinear adaptive filter is utilized. To alleviate this problem, we combine a basis-generic expansion of the memoryless nonlinearity into semi-blind source separation (SBSS). By regarding all the basis functions of the far-end input signal as the known equivalent reference signals, an SBSS updating algorithm is derived following the constrained scaled natural gradient strategy. Unlike the commonly utilized adaptive algorithm, the proposed SBSS is based on the independence between the near-end signal and the reference signals, and is less sensitive to the mismatch of nonlinearity between the numerical and actual models. Experimental results show that the proposed method outperforms conventional methods in terms of echo return loss enhancement (ERLE) and near-end speech quality evaluated by perceptual evaluation of speech quality (PESQ) and short-time objective intelligibility (STOI).