Independent Component Analysis (ICA) is intended to recover the mutually independent sources from their linear mixtures, and F astICA is one of the most successful ICA algorithms. Although it seems reasonable to improve the performance of F astICA by introducing more nonlinear functions to the negentropy estimation, the original fixed-point method (approximate Newton method) in F astICA degenerates under this circumstance. To alleviate this problem, we propose a novel method based on the second-order approximation of minimum discrimination information (MDI). The joint maximization in our method is consisted of minimizing single weighted least squares and seeking unmixing matrix by the fixed-point method. Experimental results validate its efficiency compared with other popular ICA algorithms.