This article proposes the concept of channel knowledge map (CKM) as an enabler towards environment-aware wireless communications. CKM is a site-specific database, tagged with the locations of the transmitters and/or receivers, that contains whatever channel-related information useful to enhance environmental-awareness and facilitate or even obviate sophisticated real-time channel state information (CSI) acquisition. Therefore, CKM is expected to play an important role for 6G networks targeting for super high capacity, extremely low latency, and ultra-massive connectivity, by offering potential solutions to practical challenges brought by the drastically increased channel dimensions and training overhead. In this article, the motivations of environmental-awareness enabled by CKM are firstly discussed, followed by the key techniques to build and utilize CKM. In particular, it is highlighted that CKM is especially appealing for four channel types: channels for yet-to-reach locations, channels for non-cooperative nodes, channels with large dimensions, and channels with severe hardware/processing limitations. Two case studies with extensive numerical results are presented to demonstrate the great potential of environment-aware communications enabled by CKM.