In this paper, we propose a regular vine copula based methodology for the fusion of correlated decisions. Regular vine copula is an extremely flexible and powerful graphical model to characterize complex dependence among multiple modalities. It can express a multivariate copula by using a cascade of bivariate copulas, the so-called pair copulas. Assuming that local detectors are single threshold binary quantizers and taking complex dependence among sensor decisions into account, we design an optimal fusion rule using a regular vine copula under the Neyman-Pearson framework. In order to reduce the computational complexity resulting from the complex dependence, we propose an efficient and computationally light regular vine copula based optimal fusion algorithm. Numerical experiments are conducted to demonstrate the effectiveness of our approach.