The last two decades have witnessed an exponential growth and tremendous developments in wireless technologies and systems, and their associated applications. In the recent years following 2006, there has been a great surge in interest in the newly emerging plasmonics nanotechnology because this new device technology provides tremendous synergy between electronic and photonic devices. Electronics devices are down-scalable up to the nanoscale size but have limited processor speed due to thermal and signal delay issues associated with electronic devices. On the other hand, photonic devices have extremely high speed and high data carrying capacity but are limited in size to the diffraction law such that the size of a photonic device should be equal to about half of its operational wavelength. The size mismatch between electronic devices and photonic devices inhibits the advantageous interfacing between these two device technologies and here plasmonics nanotechnology plays the important role of interfacing these two technologies. Plasmonics technology provides high speed interconnections with high data carrying capacity between nano-scale electronic devices opening a new field of research which is on-chip high speed nano-networks [28]. It is this great advantage of plasmonics technology that made it a very interesting technology for implementation for the design of a miniature real-time biosensor. In our plasmonic biosensor design, we utilized a subset of plasmonics technology which is surface plasmon wave generation in order to continuously monitor the concentration of a desired analyte.