Recently, an increasing number of multimodal (text and audio) benchmarks have emerged, primarily focusing on evaluating models' understanding capability. However, exploration into assessing generative capabilities remains limited, especially for open-ended long-form content generation. Significant challenges lie in no reference standard answer, no unified evaluation metrics and uncontrollable human judgments. In this work, we take podcast-like audio generation as a starting point and propose PodEval, a comprehensive and well-designed open-source evaluation framework. In this framework: 1) We construct a real-world podcast dataset spanning diverse topics, serving as a reference for human-level creative quality. 2) We introduce a multimodal evaluation strategy and decompose the complex task into three dimensions: text, speech and audio, with different evaluation emphasis on "Content" and "Format". 3) For each modality, we design corresponding evaluation methods, involving both objective metrics and subjective listening test. We leverage representative podcast generation systems (including open-source, close-source, and human-made) in our experiments. The results offer in-depth analysis and insights into podcast generation, demonstrating the effectiveness of PodEval in evaluating open-ended long-form audio. This project is open-source to facilitate public use: https://github.com/yujxx/PodEval.