While there has been substantial amount of work in speaker diarization recently, there are few efforts in jointly employing lexical and acoustic information for speaker segmentation. Towards that, we investigate a speaker diarization system using a sequence-to-sequence neural network trained on both lexical and acoustic features. We also propose a loss function that allows for selecting not only the speaker change points but also the best speaker at any time by allowing for different speaker groupings. We incorporate Mel Frequency Cepstral Coefficients (MFCC) as an acoustic feature alongside lexical information that are obtained from conversations from the Fisher dataset. Thus, we show that acoustics provide complementary information to the lexical modality. The experimental results show that sequence-to-sequence system trained on both word sequences and MFCC can improve on speaker diarization result compared to the system that only relies on lexical modality or the baseline MFCC-based system. In addition, we test the performance of our proposed method with Automatic Speech Recognition (ASR) transcripts. While the performance on ASR transcripts drops, the Diarization Error Rate (DER) of our proposed method still outperforms the traditional method based on Bayesian Information Criterion (BIC).