The aim of this work is to investigate the impact of crossmodal self-supervised pre-training for speech reconstruction (video-to-audio) by leveraging the natural co-occurrence of audio and visual streams in videos. We propose LipSound2 which consists of an encoder-decoder architecture and location-aware attention mechanism to map face image sequences to mel-scale spectrograms directly without requiring any human annotations. The proposed LipSound2 model is firstly pre-trained on $\sim$2400h multi-lingual (e.g. English and German) audio-visual data (VoxCeleb2). To verify the generalizability of the proposed method, we then fine-tune the pre-trained model on domain-specific datasets (GRID, TCD-TIMIT) for English speech reconstruction and achieve a significant improvement on speech quality and intelligibility compared to previous approaches in speaker-dependent and -independent settings. In addition to English, we conduct Chinese speech reconstruction on the CMLR dataset to verify the impact on transferability. Lastly, we train the cascaded lip reading (video-to-text) system by fine-tuning the generated audios on a pre-trained speech recognition system and achieve state-of-the-art performance on both English and Chinese benchmark datasets.