We propose criteria that define a trend for time series with inherent multi-scale features. We call this trend the {\it tendency} of a time series. The tendency is defined empirically by a set of criteria and captures the large-scale temporal variability of the original signal as well as the most frequent events in its histogram. Among other properties, the tendency has a variance no larger than that of the original signal; the histogram of the difference between the original signal and the tendency is as symmetric as possible; and with reduced complexity, the tendency captures essential features of the signal. To find the tendency we first use the Intrinsic Time-Scale Decomposition (ITD) of the signal, introduced in 2007 by Frei and Osorio, to produce a set of candidate tendencies. We then apply the criteria to each of the candidates to single out the one that best agrees with them. While the criteria for the tendency are independent of the signal decomposition scheme, it is found that the ITD is a simple and stable methodology, well suited for multi-scale signals. The ITD is a relatively new decomposition and little is known about its outcomes. In this study we take the first steps towards a probabilistic model of the ITD analysis of random time series. This analysis yields details concerning the universality and scaling properties of the components of the decomposition.