In many change point problems it is reasonable to assume that compared to a benchmark at a given time point $t_0$ the properties of the observed stochastic process change gradually over time for $t >t_0$. Often, these gradual changes are not of interest as long as they are small (nonrelevant), but one is interested in the question if the deviations are practically significant in the sense that the deviation of the process compared to the time $t_0$ (measured by an appropriate metric) exceeds a given threshold, which is of practical significance (relevant change). In this paper we develop novel and powerful change point analysis for detecting such deviations in a sequence of gradually varying means, which is compared with the average mean from a previous time period. Current approaches to this problem suffer from low power, rely on the selection of smoothing parameters and require a rather regular (smooth) development for the means. We develop a multiscale procedure that alleviates all these issues, validate it theoretically and demonstrate its good finite sample performance on both synthetic and real data.